Biological Availability

"Biological Availability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.

Descriptor ID	D001682
MeSH Number(s)	G03.787.151 G07.690.725.129
Concept/Terms	Biological Availability Biological Availability Availability, Biological Availabilities, Biological Biological Availabilities Biologic Availability Physiologic Availability Availability, Biologic Availabilities, Biologic Biologic Availabilities Bioavailability Bioavailabilities Availability, Physiologic Availabilities, Physiologic Physiologic Availabilities Availability Equivalency Availability Equivalency Availability Equivalencies Equivalencies, Availability Equivalency, Availability

Below are MeSH descriptors whose meaning is more general than "Biological Availability".

Biological Sciences [G]
Metabolism [G03]
Pharmacokinetics [G03.787]
Biological Availability [G03.787.151]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacokinetics [G07.690.725]
Biological Availability [G07.690.725.129]

Below are MeSH descriptors whose meaning is related to "Biological Availability".

Below are MeSH descriptors whose meaning is more specific than "Biological Availability".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Biological Availability" by people in this website by year, and whether "Biological Availability" was a major or minor topic of these publications.

Bar chart showing 81 publications over 25 distinct years, with a maximum of 8 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
2000	0	2	2
2001	0	5	5
2002	0	2	2
2003	0	4	4
2004	0	1	1
2005	0	1	1
2006	0	1	1
2007	0	2	2
2008	0	7	7
2010	0	3	3
2012	0	1	1
2013	0	5	5
2014	0	3	3
2015	0	5	5
2016	0	3	3
2017	1	1	2
2018	0	5	5
2019	0	2	2
2020	0	6	6
2021	0	8	8
2022	0	1	1
2023	0	1	1
2024	3	1	4
2025	0	5	5

Below are the most recent publications written about "Biological Availability" by people in Profiles.

Aare M, Padakanti SC, Singh M. In Vivo Pharmacodynamic and Pharmacokinetic Assessment of Cannabidiol-loaded Camel Milk Exosomes in Doxorubicin-resistant Triple-negative Breast Cancer Xenografts. AAPS PharmSciTech. 2025 Sep 11; 26(7):227.

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Wekumbura C, Hettiarachchi GM, Hargrove W, Ma Q, Newville M, Lanzirotti A, Sobin C. Mitigating lead bioaccessibility in metal(loid)s contaminated alkaline soils using soil amendments: Evaluating efficacy using in vitro bioaccessibility, sequential extraction, and synchrotron techniques. J Hazard Mater. 2025 Oct 05; 497:139742.

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Weaver C, Armah S, Bruno RS, Fletcher A, Glahn R, Herter-Aeberli I, Karosas T, Loechl CU, Lopez-Teros V, McBurney MI, Melse-Boonstra A, Novotny R, Reddy MB, Rigutto-Farebrother J, Tanumihardjo S, Udomkesmalee E, Van Den Heuvel E, Wallace T, Winichagoon P. Perspective: Framework for Developing Prediction Equations for Estimating the Absorption and Bioavailability of Nutrients from Foods. Adv Nutr. 2025 Sep; 16(9):100481.

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Sutar Y, Adams JS, Wu X, Bhoyarekar V, Garcia Diaz M, Wallace J, Dave M, Zhang QY, Date AA. Rilpivirine Ionic Liquid Nanoemulsion Augments the Oral Bioavailability of Rilpivirine and Its Delivery to the HIV Sanctuary Sites. ACS Appl Mater Interfaces. 2025 Jun 04; 17(22):31954-31970.

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Adams JS, Sutar Y, Mukkirwar S, Miglani C, Date AA. Sweetening the Deal: Sweetener-Based Ionic Liquid of Albendazole Significantly Enhances Its Solubility and Oral Bioavailability. Mol Pharm. 2025 May 05; 22(5):2568-2580.

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Wu K, Kwon SH, Zhou X, Fuller C, Wang X, Vadgama J, Wu Y. Overcoming Challenges in Small-Molecule Drug Bioavailability: A Review of Key Factors and Approaches. Int J Mol Sci. 2024 Dec 06; 25(23).

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Gangavarapu A, Tapia-Lopez LV, Sarkar B, Pena-Zacarias J, Badruddoza AZM, Nurunnabi M. Lipid nanoparticles for enhancing oral bioavailability. Nanoscale. 2024 Oct 10; 16(39):18319-18338.

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Banik SP, Kumar P, Basak P, Goel A, Ohia SE, Bagchi M, Chakraborty S, Kundu A, Bagchi D. A critical insight into the physicochemical stability of macular carotenoids with respect to their industrial production, safety profile, targeted tissue delivery, and bioavailability. Toxicol Mech Methods. 2025 Mar; 35(3):215-229.

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Bagde A, Mosley-Kellum K, Spencer S, Singh M. 3D DLP-printed cannabinoid microneedles patch and its pharmacokinetic evaluation in rats. J Pharm Pharmacol. 2024 Jun 06; 76(6):616-626.

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Zeamer AL, Salive MC, An X, Beaudoin FL, House SL, Stevens JS, Zeng D, Neylan TC, Clifford GD, Linnstaedt SD, Rauch SL, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Harris E, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Bruce SE, Kessler RC, Koenen KC, McLean SA, Bucci V, Haran JP. Association between microbiome and the development of adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure. Transl Psychiatry. 2023 11 18; 13(1):354.

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