Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease.

Kiprowska MJ, Stepanova A, Todaro DR, Galkin A, Haas A, Wilson SM, Figueiredo-Pereira ME. Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2017 06; 1863(6):1157-1170.

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subject areas

Alzheimer Disease
Animals
Cerebral Cortex
Dose-Response Relationship, Drug
Electron Transport Complex I
Mice
Mitochondria
Neurons
Neurotoxicity Syndromes
Pyrroles
Pyrrolidines
Rats
Rats, Sprague-Dawley
tau Proteins
Ubiquitin Thiolesterase
Ubiquitination

authors with profiles

Maria Figueiredo-Pereira

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