Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic ?-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1).

Sidarala V, Veluthakal R, Syeda K, Vlaar C, Newsholme P, Kowluru A. Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic ?-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1). Biochem Pharmacol. 2015 Jun 15; 95(4):301-10.

View in: PubMed

subject areas

Animals
Apoptosis
Cell Line
Enzyme Activation
Glucose
Guanosine Diphosphate
Guanosine Triphosphate
Insulin-Secreting Cells
Male
Membrane Glycoproteins
p38 Mitogen-Activated Protein Kinases
Protein Prenylation
rac1 GTP-Binding Protein
Rats, Sprague-Dawley
Reactive Oxygen Species
Signal Transduction

authors with profiles

Cornelis Vlaar