Insulin-Secreting Cells

"Insulin-Secreting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.

Descriptor ID	D050417
MeSH Number(s)	A03.734.414.131 A06.390.131 A06.407.414.087 A11.382.625.092 A11.436.294.092
Concept/Terms	Insulin-Secreting Cells Insulin-Secreting Cells Cell, Insulin-Secreting Cells, Insulin-Secreting Insulin Secreting Cells Insulin-Secreting Cell beta Cells, Pancreatic Pancreatic beta Cell beta Cell, Pancreatic Pancreatic B Cells B Cell, Pancreatic B Cells, Pancreatic Pancreatic B Cell Pancreatic beta Cells

Below are MeSH descriptors whose meaning is more general than "Insulin-Secreting Cells".

Anatomy [A]
Digestive System [A03]
Pancreas [A03.734]
Islets of Langerhans [A03.734.414]
Insulin-Secreting Cells [A03.734.414.131]
Endocrine System [A06]
Enteroendocrine Cells [A06.390]
Insulin-Secreting Cells [A06.390.131]
Endocrine Glands [A06.407]
Islets of Langerhans [A06.407.414]
Insulin-Secreting Cells [A06.407.414.087]
Cells [A11]
Endocrine Cells [A11.382]
Enteroendocrine Cells [A11.382.625]
Insulin-Secreting Cells [A11.382.625.092]
Epithelial Cells [A11.436]
Enteroendocrine Cells [A11.436.294]
Insulin-Secreting Cells [A11.436.294.092]

Below are MeSH descriptors whose meaning is related to "Insulin-Secreting Cells".

Below are MeSH descriptors whose meaning is more specific than "Insulin-Secreting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Insulin-Secreting Cells" by people in this website by year, and whether "Insulin-Secreting Cells" was a major or minor topic of these publications.

Bar chart showing 22 publications over 11 distinct years, with a maximum of 6 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	1	0	1
2008	1	0	1
2009	1	1	2
2010	1	0	1
2011	1	1	2
2012	1	0	1
2014	3	0	3
2015	4	2	6
2021	2	0	2
2023	2	0	2

Below are the most recent publications written about "Insulin-Secreting Cells" by people in Profiles.

Moss ND, Wells KL, Theis A, Kim YK, Spigelman AF, Liu X, MacDonald PE, Sussel L. Modulation of insulin secretion by RBFOX2-mediated alternative splicing. Nat Commun. 2023 Nov 25; 14(1):7732.

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Alhazzaa RA, McKinley RE, Getachew B, Tizabi Y, Heinbockel T, Csoka AB. Epigenetic Changes Induced by High Glucose in Human Pancreatic Beta Cells. J Diabetes Res. 2023; 2023:9947294.

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Khin PP, Lee JH, Jun HS. A Brief Review of the Mechanisms of ?-Cell Dedifferentiation in Type 2 Diabetes. Nutrients. 2021 May 10; 13(5).

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Zhou AX, Mondal T, Tabish AM, Abadpour S, Ericson E, Smith DM, Kn?ll R, Scholz H, Kanduri C, Tyrberg B, Althage M. The long noncoding RNA TUNAR modulates Wnt signaling and regulates human ?-cell proliferation. Am J Physiol Endocrinol Metab. 2021 04 01; 320(4):E846-E857.

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Adeyemo AA, Zaghloul NA, Chen G, Doumatey AP, Leitch CC, Hostelley TL, Nesmith JE, Zhou J, Bentley AR, Shriner D, Fasanmade O, Okafor G, Eghan B, Agyenim-Boateng K, Chandrasekharappa S, Adeleye J, Balogun W, Owusu S, Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C, Collins F, Dunston G, Rotimi CN. ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. Nat Commun. 2019 07 19; 10(1):3195.

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Keaton JM, Hellwege JN, Ng MCY, Palmer ND, Pankow JS, Fornage M, Wilson JG, Correa A, Rasmussen-Torvik LJ, Rotter JI, Chen YI, Taylor KD, Rich SS, Wagenknecht LE, Freedman BI, Bowden DW. GENOME-WIDE INTERACTION WITH SELECTED TYPE 2 DIABETES LOCI REVEALS NOVEL LOCI FOR TYPE 2 DIABETES IN AFRICAN AMERICANS. Pac Symp Biocomput. 2017; 22:242-253.

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Joseph JJ, Echouffo-Tcheugui JB, Kalyani RR, Yeh HC, Bertoni AG, Effoe VS, Casanova R, Sims M, Correa A, Wu WC, Wand GS, Golden SH. Aldosterone, Renin, and Diabetes Mellitus in African Americans: The Jackson Heart Study. J Clin Endocrinol Metab. 2016 04; 101(4):1770-8.

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Fretts AM, Follis JL, Nettleton JA, Lemaitre RN, Ngwa JS, Wojczynski MK, Kalafati IP, Varga TV, Frazier-Wood AC, Houston DK, Lahti J, Ericson U, van den Hooven EH, Mikkil? V, Kiefte-de Jong JC, Mozaffarian D, Rice K, Renstr?m F, North KE, McKeown NM, Feitosa MF, Kanoni S, Smith CE, Garcia ME, Tiainen AM, Sonestedt E, Manichaikul A, van Rooij FJ, Dimitriou M, Raitakari O, Pankow JS, Djouss? L, Province MA, Hu FB, Lai CQ, Keller MF, Per?l? MM, Rotter JI, Hofman A, Graff M, K?h?nen M, Mukamal K, Johansson I, Ordovas JM, Liu Y, M?nnist? S, Uitterlinden AG, Deloukas P, Sepp?l? I, Psaty BM, Cupples LA, Borecki IB, Franks PW, Arnett DK, Nalls MA, Eriksson JG, Orho-Melander M, Franco OH, Lehtim?ki T, Dedoussis GV, Meigs JB, Siscovick DS. Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians. Am J Clin Nutr. 2015 Nov; 102(5):1266-78.

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Veluthakal R, Tunduguru R, Arora DK, Sidarala V, Syeda K, Vlaar CP, Thurmond DC, Kowluru A. VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells. Diabetologia. 2015 Nov; 58(11):2573-81.

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Sidarala V, Veluthakal R, Syeda K, Vlaar C, Newsholme P, Kowluru A. Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic ?-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1). Biochem Pharmacol. 2015 Jun 15; 95(4):301-10.

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