Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids.

Harbuzariu A, Pitts S, Cespedes JC, Harp KO, Nti A, Shaw AP, Liu M, Stiles JK. Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids. Sci Rep. 2019 12 16; 9(1):19162.

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subject areas

Apoptosis
Brain Injuries
Brain-Derived Neurotrophic Factor
Cell Differentiation
Cells, Cultured
Cerebral Cortex
Chemokine CXCL12
Heme
Humans
Induced Pluripotent Stem Cells
Inflammation
Malaria, Cerebral
Models, Biological
Neuregulin-1
Organoids
Receptors, CXCR3
Umbilical Cord

authors with profiles

Jonathan K. Stiles

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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