WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork.

Sharma S, Otterlei M, Sommers JA, Driscoll HC, Dianov GL, Kao HI, Bambara RA, Brosh RM. WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork. Mol Biol Cell. 2004 Feb; 15(2):734-50.

View in: PubMed

subject areas

DNA Helicases
DNA Replication
Electrophoretic Mobility Shift Assay
Exodeoxyribonucleases
Flap Endonucleases
Fluorescence Resonance Energy Transfer
Hela Cells
Humans
Protein Binding
Recombinant Proteins
RecQ Helicases

authors with profiles

Sudha Sharma

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support