Caspase 3

"Caspase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

Descriptor ID	D053148
MeSH Number(s)	D08.811.277.656.262.500.126.350.300 D08.811.277.656.300.200.126.350.300 D12.644.360.075.405.350.300 D12.776.476.075.405.350.300
Concept/Terms	Caspase 3 Caspase 3 CASP3 Caspase-3 Apopain Procaspase-3 Procaspase-3 Procaspase 3 Pro-Caspase-3 Pro Caspase 3

Below are MeSH descriptors whose meaning is more general than "Caspase 3".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Cysteine Proteases [D08.811.277.656.262]
Cysteine Endopeptidases [D08.811.277.656.262.500]
Caspases [D08.811.277.656.262.500.126]
Caspases, Effector [D08.811.277.656.262.500.126.350]
Caspase 3 [D08.811.277.656.262.500.126.350.300]
Endopeptidases [D08.811.277.656.300]
Cysteine Endopeptidases [D08.811.277.656.300.200]
Caspases [D08.811.277.656.300.200.126]
Caspases, Effector [D08.811.277.656.300.200.126.350]
Caspase 3 [D08.811.277.656.300.200.126.350.300]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Apoptosis Regulatory Proteins [D12.644.360.075]
Caspases [D12.644.360.075.405]
Caspases, Effector [D12.644.360.075.405.350]
Caspase 3 [D12.644.360.075.405.350.300]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Apoptosis Regulatory Proteins [D12.776.476.075]
Caspases [D12.776.476.075.405]
Caspases, Effector [D12.776.476.075.405.350]
Caspase 3 [D12.776.476.075.405.350.300]

Below are MeSH descriptors whose meaning is related to "Caspase 3".

Below are MeSH descriptors whose meaning is more specific than "Caspase 3".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Caspase 3" by people in this website by year, and whether "Caspase 3" was a major or minor topic of these publications.

Bar chart showing 146 publications over 23 distinct years, with a maximum of 12 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	2	2
2002	0	6	6
2003	0	4	4
2004	0	5	5
2005	0	6	6
2006	2	8	10
2007	3	3	6
2008	0	9	9
2009	1	9	10
2010	1	10	11
2011	0	12	12
2012	1	5	6
2013	2	6	8
2014	0	6	6
2015	0	9	9
2016	1	7	8
2017	1	6	7
2018	2	6	8
2019	0	2	2
2021	0	5	5
2022	0	2	2
2023	0	3	3

Below are the most recent publications written about "Caspase 3" by people in Profiles.

Ii T, Chambers JK, Nakashima K, Goto-Koshino Y, Uchida K. Intraepithelial lymphocytes are associated with epithelial injury in feline intestinal T-cell lymphoma. J Vet Med Sci. 2024 Jan 26; 86(1):101-110.

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Adinew GM, Messeha S, Taka E, Ahmed SA, Soliman KFA. The Role of Apoptotic Genes and Protein-Protein Interactions in Triple-negative Breast Cancer. Cancer Genomics Proteomics. 2023 May-Jun; 20(3):247-272.

View in: PubMed
Abbasloo E, Amiresmaili S, Shirazpour S, Khaksari M, Kobeissy F, Thomas TC. Satureja khuzistanica Jamzad essential oil and pure carvacrol attenuate TBI-induced inflammation and apoptosis via NF-?B and caspase-3 regulation in the male rat brain. Sci Rep. 2023 Mar 23; 13(1):4780.

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Chhikara A, Roayapalley PK, Sakagami H, Amano S, Satoh K, Uesawa Y, Das U, Das S, Borrego EA, Guerena CD, Hernandez CR, Aguilera RJ, Dimmock JR. Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity. Molecules. 2022 Oct 09; 27(19).

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Banerjee S, Mishra S, Xu W, Thompson WE, Chowdhury I. Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell. J Ovarian Res. 2022 Jul 26; 15(1):86.

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Contreras L, Medina S, Schiaffino Bustamante AY, Borrego EA, Valenzuela CA, Das U, Karki SS, Dimmock JR, Aguilera RJ. Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms. Pharmacol Rep. 2022 Feb; 74(1):159-174.

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Wang B, Qian JY, Tang TT, Lin LL, Yu N, Guo HL, Ni WJ, Lv LL, Wen Y, Li ZL, Wu M, Cao JY, Liu BC. VDR/Atg3 Axis Regulates Slit Diaphragm to Tight Junction Transition via p62-Mediated Autophagy Pathway in Diabetic Nephropathy. Diabetes. 2021 11; 70(11):2639-2651.

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Trotta MC, Gharbia S, Herman H, Mladin B, Hermenean A, Balta C, Cotoraci C, Peteu VE, Gesualdo C, Petrillo F, Galdiero M, Alfano R, Gherghiceanu M, D'Amico M, Rossi S, Hermenean A. Sex and Age-Related Differences in Neuroinflammation and Apoptosis in Balb/c Mice Retina Involve Resolvin D1. Int J Mol Sci. 2021 Jun 11; 22(12).

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Plassmeyer M, Alpan O, Corley MJ, Premeaux TA, Lillard K, Coatney P, Vaziri T, Michalsky S, Pang APS, Bukhari Z, Yeung ST, Evering TH, Naughton G, Latterich M, Mudd P, Spada A, Rindone N, Loizou D, Ulrik S?nder S, Ndhlovu LC, Gupta R. Caspases and therapeutic potential of caspase inhibitors in moderate-severe SARS-CoV-2 infection and long COVID. Allergy. 2022 01; 77(1):118-129.

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Ghoneum MH, El Sayed NS. Protective Effect of Biobran/MGN-3 against Sporadic Alzheimer's Disease Mouse Model: Possible Role of Oxidative Stress and Apoptotic Pathways. Oxid Med Cell Longev. 2021; 2021:8845064.

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