Fragile X Mental Retardation Protein
"Fragile X Mental Retardation Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
| Descriptor ID |
D051860
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| MeSH Number(s) |
D12.776.157.725.061 D12.776.631.299 D12.776.664.962.124
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fragile X Mental Retardation Protein".
Below are MeSH descriptors whose meaning is more specific than "Fragile X Mental Retardation Protein".
This graph shows the total number of publications written about "Fragile X Mental Retardation Protein" by people in this website by year, and whether "Fragile X Mental Retardation Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fragile X Mental Retardation Protein" by people in Profiles.
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Conca Dioguardi C, Uslu B, Haynes M, Kurus M, Gul M, Miao DQ, De Santis L, Ferrari M, Bellone S, Santin A, Giulivi C, Hoffman G, Usdin K, Johnson J. Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency. Mol Hum Reprod. 2016 06; 22(6):384-96.
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Alpatov R, Lesch BJ, Nakamoto-Kinoshita M, Blanco A, Chen S, St?tzer A, Armache KJ, Simon MD, Xu C, Ali M, Murn J, Prisic S, Kutateladze TG, Vakoc CR, Min J, Kingston RE, Fischle W, Warren ST, Page DC, Shi Y. A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response. Cell. 2014 May 08; 157(4):869-81.
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Hoffman GE, Le WW, Entezam A, Otsuka N, Tong ZB, Nelson L, Flaws JA, McDonald JH, Jafar S, Usdin K. Ovarian abnormalities in a mouse model of fragile X primary ovarian insufficiency. J Histochem Cytochem. 2012 Jun; 60(6):439-56.
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Adams-Cioaba MA, Guo Y, Bian C, Amaya MF, Lam R, Wasney GA, Vedadi M, Xu C, Min J. Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2. PLoS One. 2010 Nov 02; 5(11):e13559.
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Yun SW, Platholi J, Flaherty MS, Fu W, Kottmann AH, Toth M. Fmrp is required for the establishment of the startle response during the critical period of auditory development. Brain Res. 2006 Sep 19; 1110(1):159-65.