"Charybdotoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 37-amino acid residue peptide isolated from the scorpion Leiurus quinquestriatus hebraeus. It is a neurotoxin that inhibits calcium activated potassium channels.
| Descriptor ID |
D018999
|
| MeSH Number(s) |
D12.644.115 D20.888.065.830.150 D23.946.833.065.830.150
|
| Concept/Terms |
Charybdotoxin- Charybdotoxin
- CTX Toxin
- Toxin, CTX
- Quinquestriatus Toxin
- Toxin, Quinquestriatus
- ChTX
|
Below are MeSH descriptors whose meaning is more general than "Charybdotoxin".
Below are MeSH descriptors whose meaning is more specific than "Charybdotoxin".
This graph shows the total number of publications written about "Charybdotoxin" by people in this website by year, and whether "Charybdotoxin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Charybdotoxin" by people in Profiles.
-
Vel?zquez-Marrero C, Seale GE, Treistman SN, Martin GE. Large conductance voltage- and Ca2+-gated potassium (BK) channel ?4 subunit influences sensitivity and tolerance to alcohol by altering its response to kinases. J Biol Chem. 2014 Oct 17; 289(42):29261-72.
-
Bergeron ZL, Bingham JP. Scorpion toxins specific for potassium (K+) channels: a historical overview of peptide bioengineering. Toxins (Basel). 2012 Nov 01; 4(11):1082-119.
-
Feinberg-Zadek PL, Treistman SN. Beta-subunits are important modulators of the acute response to alcohol in human BK channels. Alcohol Clin Exp Res. 2007 May; 31(5):737-44.
-
Hayoz S, B?ny JL, Bychkov R. Intracellular cAMP: the "switch" that triggers on "spontaneous transient outward currents" generation in freshly isolated myocytes from thoracic aorta. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1502-9.
-
Bychkov R, Burnham MP, Richards GR, Edwards G, Weston AH, F?l?tou M, Vanhoutte PM. Characterization of a charybdotoxin-sensitive intermediate conductance Ca2+-activated K+ channel in porcine coronary endothelium: relevance to EDHF. Br J Pharmacol. 2002 Dec; 137(8):1346-54.