"Clonal Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.
| Descriptor ID |
D017637
|
| MeSH Number(s) |
G12.535.425.120
|
| Concept/Terms |
Clonal Deletion- Clonal Deletion
- Clonal Deletions
- Deletion, Clonal
- Deletions, Clonal
Clonal Abortion- Clonal Abortion
- Abortion, Clonal
- Abortions, Clonal
- Clonal Abortions
|
Below are MeSH descriptors whose meaning is more general than "Clonal Deletion".
Below are MeSH descriptors whose meaning is more specific than "Clonal Deletion".
This graph shows the total number of publications written about "Clonal Deletion" by people in this website by year, and whether "Clonal Deletion" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clonal Deletion" by people in Profiles.
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Shanker A, Buferne M, Schmitt-Verhulst AM. Cooperative action of CD8 T lymphocytes and natural killer cells controls tumour growth under conditions of restricted T-cell receptor diversity. Immunology. 2010 Jan; 129(1):41-54.
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Murata K, Nose M, Ndhlovu LC, Sato T, Sugamura K, Ishii N. Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases. J Immunol. 2002 Oct 15; 169(8):4628-36.
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Benson JM, Campbell KA, Guan Z, Gienapp IE, Stuckman SS, Forsthuber T, Whitacre CC. T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. J Clin Invest. 2000 Oct; 106(8):1031-8.