"Self Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.
| Descriptor ID |
D017634
|
| MeSH Number(s) |
G12.535.425.800
|
| Concept/Terms |
Self Tolerance- Self Tolerance
- Self Tolerances
- Tolerance, Self
- Tolerances, Self
|
Below are MeSH descriptors whose meaning is more general than "Self Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Self Tolerance".
This graph shows the total number of publications written about "Self Tolerance" by people in this website by year, and whether "Self Tolerance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Self Tolerance" by people in Profiles.
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Maggadottir SM, Sullivan KE. The intersection of immune deficiency and autoimmunity. Curr Opin Rheumatol. 2014 Sep; 26(5):570-8.
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Martinez M, Samms M, Hendrix TM, Adeosun O, Pezzano M, Guyden JC. Thymic nurse cell multicellular complexes in HY-TCR transgenic mice demonstrate their association with MHC restriction. Exp Biol Med (Maywood). 2007 Jun; 232(6):780-8.
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Agersborg SS, Garza KM, Tung KS. Intestinal parasitism terminates self tolerance and enhances neonatal induction of autoimmune disease and memory. Eur J Immunol. 2001 Mar; 31(3):851-9.
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Garza KM, Agersborg SS, Baker E, Tung KS. Persistence of physiological self antigen is required for the regulation of self tolerance. J Immunol. 2000 Apr 15; 164(8):3982-9.