"Interleukin-9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional cytokine secreted by primarily by activated TH2 CELLS that may play a role as a regulator of allergic INFLAMMATION. It has been shown to enhance the growth and CELL DIFFERENTIATION of MAST CELLS, and can act on a variety of other immune cells.
| Descriptor ID |
D016906
|
| MeSH Number(s) |
D12.644.276.374.465.377 D12.776.467.374.465.312 D23.529.374.465.377
|
| Concept/Terms |
Interleukin-9- Interleukin-9
- Interleukin 9
- T-Cell Growth Factor P40
- T Cell Growth Factor P40
- P40 T-Cell Growth Factor
- P40 T Cell Growth Factor
- IL-9
- IL9
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-9".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-9".
This graph shows the total number of publications written about "Interleukin-9" by people in this website by year, and whether "Interleukin-9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
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Below are the most recent publications written about "Interleukin-9" by people in Profiles.
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Schwalm K, Stevens JF, Jiang Z, Schuyler MR, Schrader R, Randell SH, Green FH, Tesfaigzi Y. Expression of the proapoptotic protein Bax is reduced in bronchial mucous cells of asthmatic subjects. Am J Physiol Lung Cell Mol Physiol. 2008 Jun; 294(6):L1102-9.
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Cheng H, Ross JA, Frost JA, Kirken RA. Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity. Mol Cell Biol. 2008 Apr; 28(7):2271-82.
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Xiang J, Rir-Sim-Ah J, Tesfaigzi Y. IL-9 and IL-13 induce mucous cell metaplasia that is reduced by IFN-gamma in a Bax-mediated pathway. Am J Respir Cell Mol Biol. 2008 Mar; 38(3):310-7.
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Qiu L, Lai R, Lin Q, Lau E, Thomazy DM, Calame D, Ford RJ, Kwak LW, Kirken RA, Amin HM. Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells. Blood. 2006 Oct 01; 108(7):2407-15.
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Nagy ZS, Wang Y, Erwin-Cohen RA, Aradi J, Monia B, Wang LH, Stepkowski SM, Rui H, Kirken RA. Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways. J Leukoc Biol. 2002 Oct; 72(4):819-28.
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Yen CH, Yang YC, Ruscetti SK, Kirken RA, Dai RM, Li CC. Involvement of the ubiquitin-proteasome pathway in the degradation of nontyrosine kinase-type cytokine receptors of IL-9, IL-2, and erythropoietin. J Immunol. 2000 Dec 01; 165(11):6372-80.