Eukaryotic Initiation Factor-2

"Eukaryotic Initiation Factor-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Eukaryotic initiation factor of protein synthesis. In higher eukaryotes the factor consists of three subunits: alpha, beta, and gamma. As initiation proceeds, eIF-2 forms a ternary complex with Met-tRNAi and GTP.

Descriptor ID	D015852
MeSH Number(s)	D12.776.835.725.868.249
Concept/Terms	Eukaryotic Initiation Factor-2 Eukaryotic Initiation Factor-2 Eukaryotic Initiation Factor 2 Initiation Factor-2, Eukaryotic Peptide Initiation Factor EIF-2 Peptide Initiation Factor EIF 2 Eukaryotic Peptide Initiation Factor-2 Eukaryotic Peptide Initiation Factor 2 EIF-2 EIF 2 EIF2 Eukaryotic Initiation Factor-2, beta Subunit Eukaryotic Initiation Factor-2, beta Subunit Eukaryotic Initiation Factor 2, beta Subunit EIF-2beta EIF 2beta EIF-2 beta EIF 2 beta Eukaryotic Initiation Factor-2, gamma Subunit Eukaryotic Initiation Factor-2, gamma Subunit Eukaryotic Initiation Factor 2, gamma Subunit EIF-2gamma EIF 2gamma EIF-2 gamma EIF 2 gamma Eukaryotic Initiation Factor-2, alpha Subunit Eukaryotic Initiation Factor-2, alpha Subunit Eukaryotic Initiation Factor 2, alpha Subunit EIF-2alpha EIF 2alpha EIF-2 alpha EIF 2 alpha

Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Ribosomal Proteins [D12.776.835]
Peptide Initiation Factors [D12.776.835.725]
Eukaryotic Initiation Factors [D12.776.835.725.868]
Eukaryotic Initiation Factor-2 [D12.776.835.725.868.249]

Below are MeSH descriptors whose meaning is related to "Eukaryotic Initiation Factor-2".

Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Eukaryotic Initiation Factor-2" by people in this website by year, and whether "Eukaryotic Initiation Factor-2" was a major or minor topic of these publications.

Bar chart showing 10 publications over 6 distinct years, with a maximum of 3 publications in 2008 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
2008	2	1	3
2009	0	1	1
2013	1	0	1
2015	0	1	1
2016	2	1	3

Below are the most recent publications written about "Eukaryotic Initiation Factor-2" by people in Profiles.

Tan GM, Lim HJ, Yeow TC, Movahed E, Looi CY, Gupta R, Arulanandam BP, Abu Bakar S, Sabet NS, Chang LY, Wong WF. Temporal proteomic profiling of Chlamydia trachomatis-infected HeLa-229 human cervical epithelial cells. Proteomics. 2016 05; 16(9):1347-60.

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Sakae N, Liu CC, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, Tachibana M, Younkin L, Kurti A, Carrasquillo MM, Zou F, Sevlever D, Bisceglio G, Gan M, Fol R, Knight P, Wang M, Han X, Fryer JD, Fitzgerald ML, Ohyagi Y, Younkin SG, Bu G, Kanekiyo T. ABCA7 Deficiency Accelerates Amyloid-? Generation and Alzheimer's Neuronal Pathology. J Neurosci. 2016 Mar 30; 36(13):3848-59.

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Yamauchi Y, Riel JM, Ruthig VA, Ortega EA, Mitchell MJ, Ward MA. Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction. Science. 2016 Jan 29; 351(6272):514-6.

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Carrillo JA, He Y, Luo J, Menendez KR, Tablante NL, Zhao K, Paulson JN, Li B, Song J. Methylome Analysis in Chickens Immunized with Infectious Laryngotracheitis Vaccine. PLoS One. 2015; 10(6):e0100476.

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Yamauchi Y, Riel JM, Stoytcheva Z, Ward MA. Two Y genes can replace the entire Y chromosome for assisted reproduction in the mouse. Science. 2014 Jan 03; 343(6166):69-72.

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Elcheva I, Goswami S, Noubissi FK, Spiegelman VS. CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation. Mol Cell. 2009 Jul 31; 35(2):240-6.

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Ozpolat B, Akar U, Zorrilla-Calancha I, Vivas-Mejia P, Acevedo-Alvarez M, Lopez-Berestein G. Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Apoptosis. 2008 Jul; 13(7):915-28.

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Pervin S, Tran AH, Zekavati S, Fukuto JM, Singh R, Chaudhuri G. Increased susceptibility of breast cancer cells to stress mediated inhibition of protein synthesis. Cancer Res. 2008 Jun 15; 68(12):4862-74.

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Wu D, Yang H, Zhao Y, Sharan C, Goodwin JS, Zhou L, Guo Y, Guo Z. 2-Aminopurine inhibits lipid accumulation induced by apolipoprotein E-deficient lipoprotein in macrophages: potential role of eukaryotic initiation factor-2alpha phosphorylation in foam cell formation. J Pharmacol Exp Ther. 2008 Aug; 326(2):395-405.

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Dong J, Qiu H, Garcia-Barrio M, Anderson J, Hinnebusch AG. Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain. Mol Cell. 2000 Aug; 6(2):269-79.

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