Diabetes Mellitus, Type 1

"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Descriptor ID	D003922
MeSH Number(s)	C18.452.394.750.124 C19.246.267 C20.111.327
Concept/Terms	Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus, Brittle Brittle Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus, Insulin Dependent Insulin-Dependent Diabetes Mellitus Diabetes Mellitus, Juvenile-Onset Diabetes Mellitus, Juvenile Onset Juvenile-Onset Diabetes Mellitus Diabetes Mellitus, Ketosis-Prone Diabetes Mellitus, Ketosis Prone Ketosis-Prone Diabetes Mellitus Juvenile-Onset Diabetes Diabetes, Juvenile-Onset Juvenile Onset Diabetes Diabetes Mellitus, Type I Diabetes Mellitus, Sudden-Onset Diabetes Mellitus, Sudden Onset Mellitus, Sudden-Onset Diabetes Sudden-Onset Diabetes Mellitus Type 1 Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent, 1 Insulin-Dependent Diabetes Mellitus 1 Insulin Dependent Diabetes Mellitus 1 Type 1 Diabetes Diabetes, Type 1 IDDM Diabetes, Autoimmune Diabetes, Autoimmune Autoimmune Diabetes

Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Glucose Metabolism Disorders [C18.452.394]
Diabetes Mellitus [C18.452.394.750]
Diabetes Mellitus, Type 1 [C18.452.394.750.124]
Endocrine System Diseases [C19]
Diabetes Mellitus [C19.246]
Diabetes Mellitus, Type 1 [C19.246.267]
Immune System Diseases [C20]
Autoimmune Diseases [C20.111]
Diabetes Mellitus, Type 1 [C20.111.327]

Below are MeSH descriptors whose meaning is related to "Diabetes Mellitus, Type 1".

Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".

Diabetes Mellitus, Type 1
Wolfram Syndrome

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in this website by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.

Bar chart showing 73 publications over 27 distinct years, with a maximum of 6 publications in 2012 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1998	1	0	1
1999	0	1	1
2000	3	0	3
2001	2	1	3
2002	2	0	2
2003	3	2	5
2004	3	0	3
2005	1	0	1
2007	0	1	1
2008	2	0	2
2009	1	0	1
2010	2	0	2
2011	1	0	1
2012	5	1	6
2014	4	0	4
2015	3	1	4
2016	4	0	4
2017	2	0	2
2018	3	0	3
2019	2	0	2
2020	3	0	3
2021	3	0	3
2022	2	0	2
2023	2	0	2
2024	3	3	6
2025	5	0	5

Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles.

Lu CC, Chang CH, Chou JC, Yu PL, Wang PS. Regulatory mechanism of ghrelin on testosterone secretion in type 1 diabetic rats. Reprod Fertil. 2025 Jul 01; 6(3).

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Jeddi S, Kashfi K, Ghasemi A. The potential role of nitrate, a nitric oxide donor, in the prevention and treatment of diabetic osteoporosis. Front Endocrinol (Lausanne). 2025; 16:1480838.

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Sobhani NC, Huang Y, Venkatesh KK, Wright JD, Friedman AM, Wen T. Diabetes Technology Use in Pregnancies with Type 1 Diabetes in the United States from 2009 to 2020. Am J Perinatol. 2026 Mar; 43(4):453-460.

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Shao H, Thorpe LE, Islam S, Bian J, Guo Y, Li P, Bost S, Dabelea D, Conway R, Crume T, Schwartz BS, Hirsch AG, Allen KS, Dixon BE, Grannis SJ, Lustigova E, Reynolds K, Rosenman M, Zhong VW, Wong A, Rivera P, Le T, Akerman M, Conderino S, Rajan A, Liese AD, Rudisill C, Obeid JS, Ewing JA, Bailey C, Mendonca EA, Zaganjor I, Rolka D, Imperatore G, Pavkov ME, Divers J. Developing a Computable Phenotype for Identifying Children, Adolescents, and Young Adults With Diabetes Using Electronic Health Records in the DiCAYA Network. Diabetes Care. 2025 Jun 01; 48(6):914-921.

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Nicholas CA, Tensun FA, Evans SA, Toole KP, Prendergast JE, Broncucia H, Hesselberth JR, Gottlieb PA, Wells KL, Smith MJ. Activated polyreactive B cells are clonally expanded in autoantibody positive and patients with recent-onset type 1 diabetes. Cell Rep. 2025 Apr 22; 44(4):115425.

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Vaishnav MS, Kumari N, Srikanta S, Simha V, Krishnaswamy PR, Bhat N. Truncated Albumins as Novel Surrogate Biomarkers in Diabetes Therapy: Epiphenomena and Potential Clinical Applications. Metab Syndr Relat Disord. 2024 Dec; 22(10):743-752.

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Davidson MB, Davidson SJ. Real-world evidence for computerized insulin dose-adjustment algorithms in the effective use of continuous glucose monitoring by primary care clinicians. Diabetes Obes Metab. 2024 Aug; 26(8):3475-3477.

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Darshi M, Kugathasan L, Maity S, Sridhar VS, Fernandez R, Limonte CP, Grajeda BI, Saliba A, Zhang G, Drel VR, Kim JJ, Montellano R, Tumova J, Montemayor D, Wang Z, Liu JJ, Wang J, Perkins BA, Lytvyn Y, Natarajan L, Lim SC, Feldman H, Toto R, Sedor JR, Patel J, Waikar SS, Brown J, Osman Y, He J, Chen J, Reeves WB, de Boer IH, Roy S, Vallon V, Hallan S, Gelfond JA, Cherney DZ, Sharma K. Glycolytic lactate in diabetic kidney disease. JCI Insight. 2024 Jun 10; 9(11).

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Hixon JC, Rivas Zarete JI, White J, Hilaire M, Muhammad A, Yusuf AP, Adu-Addai B, Yates CC, Mahavadi S. Epigenetic Modulation of GPER Expression in Gastric and Colonic Smooth Muscle of Male and Female Non-Obese Diabetic (NOD) Mice: Insights into H3K4me3 and H3K27ac Modifications. Int J Mol Sci. 2024 May 11; 25(10).

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Vaishnav MS, Kumari N, Srikanta S, Simha V, Krishnaswamy PR, Balaram P, Bhat N. Albumin Oxidation and Albumin Glycation Discordance During Type 2 Diabetes Therapy: Biological and Clinical Implications. Metab Syndr Relat Disord. 2024 Jun; 22(5):372-384.

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