Diabetes Mellitus, Type 1

"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Descriptor ID	D003922
MeSH Number(s)	C18.452.394.750.124 C19.246.267 C20.111.327
Concept/Terms	Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus, Brittle Brittle Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus, Insulin Dependent Insulin-Dependent Diabetes Mellitus Diabetes Mellitus, Juvenile-Onset Diabetes Mellitus, Juvenile Onset Juvenile-Onset Diabetes Mellitus Diabetes Mellitus, Ketosis-Prone Diabetes Mellitus, Ketosis Prone Ketosis-Prone Diabetes Mellitus Juvenile-Onset Diabetes Diabetes, Juvenile-Onset Juvenile Onset Diabetes Diabetes Mellitus, Type I Diabetes Mellitus, Sudden-Onset Diabetes Mellitus, Sudden Onset Mellitus, Sudden-Onset Diabetes Sudden-Onset Diabetes Mellitus Type 1 Diabetes Mellitus Diabetes Mellitus, Insulin-Dependent, 1 Insulin-Dependent Diabetes Mellitus 1 Insulin Dependent Diabetes Mellitus 1 Type 1 Diabetes Diabetes, Type 1 IDDM Diabetes, Autoimmune Diabetes, Autoimmune Autoimmune Diabetes

Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Glucose Metabolism Disorders [C18.452.394]
Diabetes Mellitus [C18.452.394.750]
Diabetes Mellitus, Type 1 [C18.452.394.750.124]
Endocrine System Diseases [C19]
Diabetes Mellitus [C19.246]
Diabetes Mellitus, Type 1 [C19.246.267]
Immune System Diseases [C20]
Autoimmune Diseases [C20.111]
Diabetes Mellitus, Type 1 [C20.111.327]

Below are MeSH descriptors whose meaning is related to "Diabetes Mellitus, Type 1".

Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".

Diabetes Mellitus, Type 1
Wolfram Syndrome

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in this website by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.

Bar chart showing 46 publications over 26 distinct years, with a maximum of 5 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1998	1	0	1
1999	0	1	1
2000	2	0	2
2001	1	1	2
2002	1	0	1
2003	2	1	3
2004	3	0	3
2005	1	0	1
2007	0	1	1
2008	1	0	1
2009	1	0	1
2010	2	0	2
2011	1	0	1
2012	4	1	5
2014	2	0	2
2015	3	1	4
2016	3	0	3
2017	1	0	1
2018	1	0	1
2019	1	0	1
2020	3	0	3
2021	1	0	1
2022	2	0	2
2023	1	0	1
2024	1	0	1

Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles.

Kim YK, Kim YR, Wells KL, Sarbaugh D, Guney M, Tsai CF, Zee T, Karsenty G, Nakayasu ES, Sussel L. PTPN2 Regulates Metabolic Flux to Affect ?-Cell Susceptibility to Inflammatory Stress. Diabetes. 2024 Mar 01; 73(3):434-447.

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Stensland ZC, Magera CA, Broncucia H, Gomez BD, Rios-Guzman NM, Wells KL, Nicholas CA, Rihanek M, Hunter MJ, Toole KP, Gottlieb PA, Smith MJ. Identification of an anergic BND cell-derived activated B cell population (BND2) in young-onset type 1 diabetes patients. J Exp Med. 2023 08 07; 220(8).

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Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, Davidson HW. Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mol Metab. 2022 12; 66:101632.

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Xu NY, Nguyen KT, DuBord AY, Pickup J, Sherr JL, Teymourian H, Cengiz E, Ginsberg BH, Cobelli C, Ahn D, Bellazzi R, Bequette BW, Gandrud Pickett L, Parks L, Spanakis EK, Masharani U, Akturk HK, Melish JS, Kim S, Kang GE, Klonoff DC. Diabetes Technology Meeting 2021. J Diabetes Sci Technol. 2022 07; 16(4):1016-1056.

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Baxter SK, Walsh T, Casadei S, Eckert MM, Allenspach EJ, Hagin D, Segundo G, Lee MK, Gulsuner S, Shirts BH, Sullivan KE, Keller MD, Torgerson TR, King MC. Molecular diagnosis of childhood immune dysregulation, polyendocrinopathy, and enteropathy, and implications for clinical management. J Allergy Clin Immunol. 2022 01; 149(1):327-339.

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Eltayeb-Elsheikh N, Khalil E, Mubasher M, AlJurayyan A, AlHarthi H, Omer WH, Elghazali I, Sherbeeni SM, Alghofely MA, Ilonen J, Elghazali G. Association of HLA-DR-DQ alleles, haplotypes, and diplotypes with type 1 diabetes in Saudis. Diabetes Metab Res Rev. 2020 11; 36(8):e3345.

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Melish JS. Covid-19 and Diabetes in Hawaii. J Diabetes Sci Technol. 2020 Jul; 14(4):756-757.

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Desouza CV, Holcomb RG, Rosenstock J, Frias JP, Hsia SH, Klein EJ, Zhou R, Kohzuma T, Fonseca VA. Results of a Study Comparing Glycated Albumin to Other Glycemic Indices. J Clin Endocrinol Metab. 2020 03 01; 105(3).

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Davidson MB. The Case for Using Human Insulin. Am J Med. 2020 02; 133(2):e23-e24.

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Sommese L, Benincasa G, Lanza M, Sorriento A, Schiano C, Lucchese R, Alfano R, Nicoletti GF, Napoli C. Novel epigenetic-sensitive clinical challenges both in type 1 and type 2 diabetes. J Diabetes Complications. 2018 Nov; 32(11):1076-1084.

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