Carbazoles

"Carbazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Benzo-indoles similar to CARBOLINES which are pyrido-indoles. In plants, carbazoles are derived from indole and form some of the INDOLE ALKALOIDS.

Descriptor ID	D002227
MeSH Number(s)	D03.633.100.473.144 D03.633.300.148
Concept/Terms	Carbazoles Carbazoles

Below are MeSH descriptors whose meaning is more general than "Carbazoles".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Carbazoles [D03.633.100.473.144]
Heterocyclic Compounds, 3-Ring [D03.633.300]
Carbazoles [D03.633.300.148]

Below are MeSH descriptors whose meaning is more specific than "Carbazoles".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carbazoles" by people in this website by year, and whether "Carbazoles" was a major or minor topic of these publications.

Bar chart showing 32 publications over 20 distinct years, with a maximum of 3 publications in 2000 and 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
2000	3	0	3
2004	1	1	2
2006	2	1	3
2007	1	0	1
2008	1	0	1
2009	0	2	2
2010	0	1	1
2012	1	1	2
2013	2	0	2
2014	1	0	1
2015	1	0	1
2016	2	0	2
2017	0	1	1
2018	1	1	2
2019	1	0	1
2020	0	1	1
2021	0	1	1
2023	0	1	1
2026	1	1	2

Below are the most recent publications written about "Carbazoles" by people in Profiles.

Parapini S, D'Alessandro S, Travaglione S, Paone S, Madera Cuevas IM, Dipol T, Zongo DWR, Figueroa V?zquez AM, Morsilli O, Fabbri A, Vlaar CP, Olivieri A. Design, synthesis and biological evaluation of Rac1-targeting carbazole-pyrimidines as host-directed antimalarials. Eur J Med Chem. 2026 Apr 15; 308:118690.

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Holliday H, Khan A, Ehteda A, Nguyen H, Ross SE, Jayatilleke N, Gopalakrishnan A, Wang E, Sanguino YC, Kavanagh D, Guo X, Liu J, Lawrence D, Sun CX, Lehmann R, Ip CK, Lee A, Rangel-Sanchez L, Li W, Salomon R, Firestein R, Weatheritt RJ, Valdes-Mora F, Dinger ME, Phoenix TN, Mayoh C, Rayner BS, Tsoli M, Ziegler DS. Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma. Sci Transl Med. 2026 Jan 14; 18(832):eadr1557.

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Mrad Y, El Jammal R, Hajjar H, Alturk S, Salah H, Chehade HD, Dandash F, Mallah Z, Kobeissy F, Habib A, Hamade E, Obeid M. Lestaurtinib (CEP-701) reduces the duration of limbic status epilepticus in periadolescent rats. Epilepsy Res. 2023 09; 195:107198.

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Borrero-Garc?a LD, Del Mar Maldonado M, Medina-Vel?zquez J, Troche-Torres AL, Velazquez L, Grafals-Ruiz N, Dharmawardhane S. Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer. BMC Cancer. 2021 Jun 01; 21(1):652.

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Zhang L, Leng TD, Yang T, Li J, Xiong ZG. Protein Kinase C Regulates ASIC1a Protein Expression and Channel Function via NF-kB Signaling Pathway. Mol Neurobiol. 2020 Nov; 57(11):4754-4766.

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Butler-Fern?ndez KM, Ramos Z, Francis-Malav? AM, Bloom J, Dharmawardhane S, Hern?ndez E. Synthesis, Anti-Cancer and Anti-Migratory Evaluation of 3,6-Dibromocarbazole and 5-Bromoindole Derivatives. Molecules. 2019 Jul 24; 24(15).

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Chitrala KN, Yang X, Nagarkatti P, Nagarkatti M. Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study. BMC Struct Biol. 2018 12 06; 18(1):15.

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Vlaar CP, Castillo-Pichardo L, Medina JI, Marrero-Serra CM, V?lez E, Ramos Z, Hern?ndez E. Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents. Bioorg Med Chem. 2018 02 15; 26(4):884-890.

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Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer. Mol Cancer Ther. 2017 05; 16(5):805-818.

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Zhuang X, Ma X, Xue X, Jiang Q, Song L, Dai L, Zhang C, Jin S, Yang K, Ding B, Wang PC, Liang XJ. A Photosensitizer-Loaded DNA Origami Nanosystem for Photodynamic Therapy. ACS Nano. 2016 Mar 22; 10(3):3486-95.

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