"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
| Descriptor ID |
D001253
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| MeSH Number(s) |
A08.637.200 A11.650.200
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 4 | 4 |
| 1994 | 2 | 0 | 2 |
| 1995 | 4 | 0 | 4 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 0 | 2 |
| 1998 | 3 | 1 | 4 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 2 | 4 |
| 2005 | 0 | 4 | 4 |
| 2006 | 3 | 3 | 6 |
| 2007 | 2 | 2 | 4 |
| 2008 | 0 | 5 | 5 |
| 2009 | 1 | 1 | 2 |
| 2010 | 8 | 5 | 13 |
| 2011 | 1 | 2 | 3 |
| 2012 | 5 | 2 | 7 |
| 2013 | 7 | 1 | 8 |
| 2014 | 4 | 2 | 6 |
| 2015 | 6 | 1 | 7 |
| 2016 | 5 | 3 | 8 |
| 2017 | 4 | 1 | 5 |
| 2018 | 2 | 3 | 5 |
| 2019 | 5 | 4 | 9 |
| 2020 | 4 | 1 | 5 |
| 2021 | 3 | 2 | 5 |
| 2022 | 3 | 2 | 5 |
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click here.
Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Kong W, Montano M, Corley MJ, Helmy E, Kobayashi H, Kinisu M, Suryawanshi R, Luo X, Royer LA, Roan NR, Ott M, Ndhlovu LC, Greene WC. Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. mBio. 2022 12 20; 13(6):e0230822.
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Cancel LM, Silas D, Bikson M, Tarbell JM. Direct current stimulation modulates gene expression in isolated astrocytes with implications for glia-mediated plasticity. Sci Rep. 2022 Oct 26; 12(1):17964.
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Pajarillo E, Demayo M, Digman A, Nyarko-Danquah I, Son DS, Aschner M, Lee E. Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice. Glia. 2022 10; 70(10):1886-1901.
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Watanabe S, Omran AA, Shao AS, Xue C, Zhang Z, Zhang J, Davies DL, Shao XM, Watanabe J, Liang J. Dihydromyricetin improves social isolation-induced cognitive impairments and astrocytic changes in mice. Sci Rep. 2022 04 07; 12(1):5899.
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Volnova A, Tsytsarev V, Ganina O, V?lez-Crespo GE, Alves JM, Ignashchenkova A, Inyushin M. The Anti-Epileptic Effects of Carbenoxolone In Vitro and In Vivo. Int J Mol Sci. 2022 Jan 08; 23(2).
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Rizor A, Pajarillo E, Son DS, Aschner M, Lee E. Manganese phosphorylates Yin Yang 1 at serine residues to repress EAAT2 in human H4 astrocytes. Toxicol Lett. 2022 Feb 01; 355:41-46.
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Rivera-Ortiz J, Pla-Tenorio J, Cruz ML, Colon K, Perez-Morales J, Rodriguez JA, Martinez-Sicari J, Noel RJ. Blockade of beta adrenergic receptors protects the blood brain barrier and reduces systemic pathology caused by HIV-1 Nef protein. PLoS One. 2021; 16(11):e0259446.
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Pajarillo E, Digman A, Nyarko-Danquah I, Son DS, Soliman KFA, Aschner M, Lee E. Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity. J Biol Chem. 2021 12; 297(6):101372.
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Malpica-Nieves CJ, Rivera Y, Rivera-Aponte DE, Phanstiel O, Veh RW, Eaton MJ, Skatchkov SN. Uptake of Biotinylated Spermine in Astrocytes: Effect of Cx43 siRNA, HIV-Tat Protein and Polyamine Transport Inhibitor on Polyamine Uptake. Biomolecules. 2021 08 11; 11(8).
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Rizor A, Pajarillo E, Nyarko-Danquah I, Digman A, Mooneyham L, Son DS, Aschner M, Lee E. Manganese-induced reactive oxygen species activate I?B kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro. Neurotoxicology. 2021 09; 86:94-103.