Below are the most recent publications written about "Antiprotozoal Agents" by people in Profiles.
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Santos CC, Zhang H, Batista MM, de Oliveira GM, Demarque KC, da Silva NL, Moreira OC, Ogungbe IV, Soeiro MNC. Phenotypic investigation of 4-nitrophenylacetyl- and 4-nitro-1H-imidazoyl-based compounds as antileishmanial agents. Parasitology. 2022 04; 149(4):490-495.
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Santos CC, Zhang H, Batista MM, de Oliveira GM, Demarque KC, da Silva-Gomes NL, Moreira OC, Ogungbe IV, Soeiro MNC. In Vitro and In Vivo Evaluation of an Adamantyl-Based Phenyl Sulfonyl Acetamide against Cutaneous Leishmaniasis Models of Leishmania amazonensis. Antimicrob Agents Chemother. 2020 11 17; 64(12).
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Rodriguez F, John SF, Iniguez E, Montalvo S, Michael K, White L, Liang D, Olaleye OA, Maldonado RA. In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors. Antimicrob Agents Chemother. 2020 05 21; 64(6).
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Zhang H, Collins J, Nyamwihura R, Crown O, Ajayi O, Ogungbe IV. Vinyl sulfone-based inhibitors of trypanosomal cysteine protease rhodesain with improved antitrypanosomal activities. Bioorg Med Chem Lett. 2020 07 15; 30(14):127217.
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Friggeri L, Hargrove TY, Rachakonda G, Blobaum AL, Fisher P, de Oliveira GM, da Silva CF, Soeiro MNC, Nes WD, Lindsley CW, Villalta F, Guengerich FP, Lepesheva GI. Sterol 14a-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae. J Med Chem. 2018 12 13; 61(23):10910-10921.
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Zhou W, Debnath A, Jennings G, Hahn HJ, Vanderloop BH, Chaudhuri M, Nes WD, Podust LM. Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. PLoS Pathog. 2018 09; 14(9):e1007245.
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Rodriguez F, Iniguez E, Pena Contreras G, Ahmed H, Costa TEMM, Skouta R, Maldonado RA. Development of Thiophene Compounds as Potent Chemotherapies for the Treatment of Cutaneous Leishmaniasis Caused by Leishmania major. Molecules. 2018 07 04; 23(7).
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Ogungbe IV, Setzer WN. The Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking Investigations. Molecules. 2016 Oct 19; 21(10).
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Herrera L, Stephens DE, D'Avila A, George KG, Arman H, Zhang Y, Perry G, Lleonart R, Larionov OV, Fern?ndez PL. Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles. Org Biomol Chem. 2016 Aug 07; 14(29):7053-60.
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Herrera LJ, Brand S, Santos A, Nohara LL, Harrison J, Norcross NR, Thompson S, Smith V, Lema C, Varela-Ramirez A, Gilbert IH, Almeida IC, Maldonado RA. Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004540.