| Item Type | Name |
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Grant
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p53-Independent Cell Death Signaling by Mitomycin DNA Adducts
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Grant
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The Role of the Mutant p53-PARP-MCM Pathway in Triple Negative Breast Cancer
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Academic Article
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p53 binds to a constitutively nucleosome free region of the mdm2 gene.
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Academic Article
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DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1.
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Academic Article
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Differential toxicity of DNA adducts of mitomycin C.
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Academic Article
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A DNA damage signal is required for p53 to activate gadd45.
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Academic Article
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Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53.
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Academic Article
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C. elegans CEP-1/p53 and BEC-1 are involved in DNA repair.
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Academic Article
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Initiation of rolling-circle replication in pT181 plasmid: initiator protein enhances cruciform extrusion at the origin.
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Academic Article
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Decarbamoyl mitomycin C (DMC) activates p53-independent ataxia telangiectasia and rad3 related protein (ATR) chromatin eviction.
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Academic Article
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Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4.
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Academic Article
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DNA-binding properties of the p53 tumor suppressor protein.
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Academic Article
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p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis.
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Academic Article
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Measurement of gene expression by translational coupling: effect of copy mutations on pT181 initiator synthesis.
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Academic Article
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A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein.
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Academic Article
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Staphylococcus aureus chromosomal mutations that decrease efficiency of Rep utilization in replication of pT181 and related plasmids.
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Academic Article
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The p53 protein is an unusually shaped tetramer that binds directly to DNA.
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Academic Article
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Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer.
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Academic Article
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A Protein in the Yeast Saccharomyces cerevisiae Presents DNA Binding Homology to the p53 Checkpoint Protein and Tumor Suppressor.
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Academic Article
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Infrared spectroscopy of human tissue. V. Infrared spectroscopic studies of myeloid leukemia (ML-1) cells at different phases of the cell cycle.
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Academic Article
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In vivo footprinting and DNA affinity chromatography for analysis of p53 DNA binding ability.
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Academic Article
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Wild-type p53 activates transcription in vitro.
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Academic Article
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Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element.
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Academic Article
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Mutant p53 forms a complex with Sp1 on HIV-LTR DNA.
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Academic Article
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Camptothecin and Zeocin can increase p53 levels during all cell cycle stages.
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Academic Article
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Differential activation of p53 by the various adducts of mitomycin C.
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Academic Article
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Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.
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Academic Article
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Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication.
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Academic Article
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Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.
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Academic Article
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Functional consequences of the interactions of the p53 tumor suppressor protein and SV40 large tumor antigen.
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Academic Article
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Mouse double minute 2 associates with chromatin in the presence of p53 and is released to facilitate activation of transcription.
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Academic Article
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Mitomycin-DNA adducts induce p53-dependent and p53-independent cell death pathways.
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Academic Article
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Disruption of the p53-Mdm2 complex by Nutlin-3 reveals different cancer cell phenotypes.
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Academic Article
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p53 represses Sp1 DNA binding and HIV-LTR directed transcription.
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Academic Article
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Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry.
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Concept
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DNA
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Concept
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DNA Damage
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Concept
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DNA Mutational Analysis
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Concept
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DNA Repair
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Concept
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DNA Replication
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Concept
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DNA-Binding Proteins
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Concept
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DNA, Bacterial
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Concept
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DNA, Neoplasm
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Concept
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DNA, Viral
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Concept
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Single-Strand Specific DNA and RNA Endonucleases
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Concept
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DNA Fingerprinting
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Concept
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DNA Primers
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Concept
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DNA Adducts
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Concept
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DNA Footprinting
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Academic Article
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Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment.
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Academic Article
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A CANCER PERSISTENT DNA REPAIR CIRCUIT DRIVEN BY MDM2, MDM4 (MDMX), AND MUTANT P53 FOR RECRUITMENT OF MDC1 AND 53BP1 TO CHROMATIN.
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