A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein.

Bargonetti J, Manfredi JJ, Chen X, Marshak DR, Prives C. A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes Dev. 1993 Dec; 7(12B):2565-74.

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subject areas

Base Sequence
Binding Sites
Humans
Molecular Sequence Data
Mutation
Oligonucleotides
Peptide Fragments
Recombinant Proteins
Thermolysin
Tumor Suppressor Protein p53

authors with profiles

Jill Bargonetti

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