Connective Tissue Growth Factor

"Connective Tissue Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.

Descriptor ID	D055513
MeSH Number(s)	D12.644.276.200.100 D12.776.467.200.100 D12.776.860.300.200.100 D23.529.237.100
Concept/Terms	Connective Tissue Growth Factor Connective Tissue Growth Factor Hypertrophic Chondrocyte-Specific Protein 24 Hypertrophic Chondrocyte Specific Protein 24 IGF-Binding Protein-Related Protein-2 IGF Binding Protein Related Protein 2 IGFBP-rP2 Insulin-Like Growth Factor Binding Protein 8 Insulin Like Growth Factor Binding Protein 8 CCN2 Protein IGFBP-8

Below are MeSH descriptors whose meaning is more general than "Connective Tissue Growth Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
CCN Intercellular Signaling Proteins [D12.644.276.200]
Connective Tissue Growth Factor [D12.644.276.200.100]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
CCN Intercellular Signaling Proteins [D12.776.467.200]
Connective Tissue Growth Factor [D12.776.467.200.100]
Scleroproteins [D12.776.860]
Extracellular Matrix Proteins [D12.776.860.300]
CCN Intercellular Signaling Proteins [D12.776.860.300.200]
Connective Tissue Growth Factor [D12.776.860.300.200.100]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
CCN Intercellular Signaling Proteins [D23.529.237]
Connective Tissue Growth Factor [D23.529.237.100]

Below are MeSH descriptors whose meaning is related to "Connective Tissue Growth Factor".

Below are MeSH descriptors whose meaning is more specific than "Connective Tissue Growth Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Connective Tissue Growth Factor" by people in this website by year, and whether "Connective Tissue Growth Factor" was a major or minor topic of these publications.

Bar chart showing 14 publications over 10 distinct years, with a maximum of 2 publications in 2006 and 2015 and 2016 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2005	0	1	1
2006	0	2	2
2007	0	1	1
2010	1	0	1
2011	1	0	1
2012	1	0	1
2015	0	2	2
2016	1	1	2
2017	1	1	2

Below are the most recent publications written about "Connective Tissue Growth Factor" by people in Profiles.

Igietseme JU, Omosun Y, Nagy T, Stuchlik O, Reed MS, He Q, Partin J, Joseph K, Ellerson D, George Z, Goldstein J, Eko FO, Bandea C, Pohl J, Black CM. Molecular Pathogenesis of Chlamydia Disease Complications: Epithelial-Mesenchymal Transition and Fibrosis. Infect Immun. 2018 01; 86(1).

View in: PubMed
Donlon TA, Morris BJ, He Q, Chen R, Masaki KH, Allsopp RC, Willcox DC, Tranah GJ, Parimi N, Evans DS, Flachsbart F, Nebel A, Kim DH, Park J, Willcox BJ. Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity. J Gerontol A Biol Sci Med Sci. 2017 Aug 01; 72(8):1038-1044.

View in: PubMed
Jang JH, Chand HS, Bruse S, Doyle-Eisele M, Royer C, McDonald J, Qualls C, Klingelhutz AJ, Lin Y, Mallampalli R, Tesfaigzi Y, Nyunoya T. Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity. COPD. 2017 Apr; 14(2):228-237.

View in: PubMed
Covington JD, Tam CS, Bajpeyi S, Galgani JE, Noland RC, Smith SR, Redman LM, Ravussin E. Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation. Med Sci Sports Exerc. 2016 Mar; 48(3):384-90.

View in: PubMed
Yan H, Chen Y, Li L, Jiang J, Wu G, Zuo Y, Zhang JH, Feng H, Yan X, Liu F. Decorin alleviated chronic hydrocephalus via inhibiting TGF-?1/Smad/CTGF pathway after subarachnoid hemorrhage in rats. Brain Res. 2016 Jan 01; 1630:241-53.

View in: PubMed
Li Y, Francia G, Zhang JY. p62/IMP2 stimulates cell migration and reduces cell adhesion in breast cancer. Oncotarget. 2015 Oct 20; 6(32):32656-68.

View in: PubMed
Chen L, Wu YG, Liu D, Lv LL, Zheng M, Ni HF, Cao YH, Liu H, Zhang P, Zhang JD, Liu BC. Urinary mRNA expression of CCN2/CCN3 as a noninvasive marker for monitoring glomerular structure changes in nondiabetic chronic kidney disease. Biomarkers. 2012 Dec; 17(8):714-20.

View in: PubMed
Chien W, O'Kelly J, Lu D, Leiter A, Sohn J, Yin D, Karlan B, Vadgama J, Lyons KM, Koeffler HP. Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis. Int J Oncol. 2011 Jun; 38(6):1741-7.

View in: PubMed
Yin D, Chen W, O'Kelly J, Lu D, Ham M, Doan NB, Xie D, Wang C, Vadgama J, Said JW, Black KL, Koeffler HP. Connective tissue growth factor associated with oncogenic activities and drug resistance in glioblastoma multiforme. Int J Cancer. 2010 Nov 15; 127(10):2257-67.

View in: PubMed
Liu BC, Li MX, Zhang JD, Liu XC, Zhang XL, Phillips AO. Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition. Am J Nephrol. 2008; 28(1):143-51.

View in: PubMed

People

Explore

Similar Concepts

Top Journals