"Chemokine CCL21" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards DENDRITIC CELLS and T-LYMPHOCYTES.
| Descriptor ID |
D054421
|
| MeSH Number(s) |
D12.644.276.374.200.110.890 D12.776.467.374.200.110.890 D23.125.300.110.890 D23.469.200.110.890 D23.529.374.200.110.890
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| Concept/Terms |
Chemokine CCL21- Chemokine CCL21
- CCL21, Chemokine
- 6Ckine
- SLC Chemokine
- Chemokine, SLC
- Exodus-2 Chemokine
- Chemokine, Exodus-2
- Exodus 2 Chemokine
- Secondary Lymphoid-Tissue Chemokine
- Chemokine, Secondary Lymphoid-Tissue
- Lymphoid-Tissue Chemokine, Secondary
- Secondary Lymphoid Tissue Chemokine
- Thymus-Derived Chemotactic Agent 4
- Thymus Derived Chemotactic Agent 4
- CCL21 Chemokine
- Chemokine, CCL21
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Below are MeSH descriptors whose meaning is more general than "Chemokine CCL21".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CCL21".
This graph shows the total number of publications written about "Chemokine CCL21" by people in this website by year, and whether "Chemokine CCL21" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Chemokine CCL21" by people in Profiles.
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Bastow CR, Bunting MD, Kara EE, McKenzie DR, Caon A, Devi S, Tolley L, Mueller SN, Frazer IH, Harvey N, Condina MR, Young C, Hoffmann P, McColl SR, Comerford I. Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration. Proc Natl Acad Sci U S A. 2021 04 27; 118(17).
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McGovern KE, Nance JP, David CN, Harrison RES, Noor S, Worth D, Landrith TA, Obenaus A, Carson MJ, Morikis D, Wilson EH. SPARC coordinates extracellular matrix remodeling and efficient recruitment to and migration of antigen-specific T cells in the brain following infection. Sci Rep. 2021 02 25; 11(1):4549.
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Carson MJ, Wilson EH. Visualizing chemokine-dependent T cell activation and migration in response to central nervous system infection. Methods Mol Biol. 2013; 1013:171-83.
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Shannon LA, McBurney TM, Wells MA, Roth ME, Calloway PA, Bill CA, Islam S, Vines CM. CCR7/CCL19 controls expression of EDG-1 in T cells. J Biol Chem. 2012 Apr 06; 287(15):11656-64.
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Shannon LA, Calloway PA, Welch TP, Vines CM. CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes. J Biol Chem. 2010 Dec 10; 285(50):38781-7.
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Ploix CC, Noor S, Crane J, Masek K, Carter W, Lo DD, Wilson EH, Carson MJ. CNS-derived CCL21 is both sufficient to drive homeostatic CD4+ T cell proliferation and necessary for efficient CD4+ T cell migration into the CNS parenchyma following Toxoplasma gondii infection. Brain Behav Immun. 2011 Jul; 25(5):883-96.
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Noor S, Habashy AS, Nance JP, Clark RT, Nemati K, Carson MJ, Wilson EH. CCR7-dependent immunity during acute Toxoplasma gondii infection. Infect Immun. 2010 May; 78(5):2257-63.
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Ploix C, Zuberi RI, Liu FT, Carson MJ, Lo DD. Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta. Int J Med Sci. 2009; 6(2):85-92.
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Byers MA, Calloway PA, Shannon L, Cunningham HD, Smith S, Li F, Fassold BC, Vines CM. Arrestin 3 mediates endocytosis of CCR7 following ligation of CCL19 but not CCL21. J Immunol. 2008 Oct 01; 181(7):4723-32.