Receptors, CCR7

"Receptors, CCR7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

CCR receptors with specificity for CHEMOKINE CCL19 and CHEMOKINE CCL21. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; and DENDRITIC CELLS.

Descriptor ID	D054400
MeSH Number(s)	D12.776.543.750.695.160.150.700 D12.776.543.750.705.852.125.150.700
Concept/Terms	Receptors, CCR7 Receptors, CCR7 CC Chemokine Receptor 7 CD197 Antigen Antigen, CD197 CCR7 Receptors CD197 Antigens Antigens, CD197 CC Chemokine Receptor CCR7

Below are MeSH descriptors whose meaning is more general than "Receptors, CCR7".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Chemokine [D12.776.543.750.695.160]
Receptors, CCR [D12.776.543.750.695.160.150]
Receptors, CCR7 [D12.776.543.750.695.160.150.700]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Chemokine [D12.776.543.750.705.852.125]
Receptors, CCR [D12.776.543.750.705.852.125.150]
Receptors, CCR7 [D12.776.543.750.705.852.125.150.700]

Below are MeSH descriptors whose meaning is related to "Receptors, CCR7".

Below are MeSH descriptors whose meaning is more specific than "Receptors, CCR7".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, CCR7" by people in this website by year, and whether "Receptors, CCR7" was a major or minor topic of these publications.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 2010 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	1	0	1
2010	2	0	2
2012	1	0	1
2016	1	0	1
2019	1	0	1
2021	0	1	1
2022	1	1	2
2024	1	0	1
2025	1	0	1

Below are the most recent publications written about "Receptors, CCR7" by people in Profiles.

Bai Y, Ren H, Leng S, Yuan M, Jiang Y, Zhang S, Wang Y, Ju M, Wang Z, Xi W, Xu L, Zheng B, Li D, Huo X, Zhu T, Zhang B, Shen L, Zhang Y, Jiang W, Zhang JH, Han B, Yao H. CD8+GZMK+CD27+CCR7+ T cells mobilized by splenic sympathetic nerves aggravate brain ischemia?reperfusion injury via CCL19-positive endothelial cells. Cell Mol Immunol. 2025 Sep; 22(9):1061-1076.

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Cardona CI, Rodriguez A, Torres VC, Sanchez A, Torres A, Vazquez AE, Wagler AE, Brissette MA, Bill CA, Vines CM. C-C Chemokine Receptor 7 Promotes T-Cell Acute Lymphoblastic Leukemia Invasion of the Central Nervous System via ?2-Integrins. Int J Mol Sci. 2024 Sep 06; 25(17).

View in: PubMed
Kroll KW, Shah SV, Lucar OA, Premeaux TA, Shikuma CM, Corley MJ, Mosher M, Woolley G, Bowler S, Ndhlovu LC, Reeves RK. Mucosal-homing natural killer cells are associated with aging in persons living with HIV. Cell Rep Med. 2022 10 18; 3(10):100773.

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Bill CA, Allen CM, Vines CM. C-C Chemokine Receptor 7 in Cancer. Cells. 2022 02 14; 11(4).

View in: PubMed
McGovern KE, Nance JP, David CN, Harrison RES, Noor S, Worth D, Landrith TA, Obenaus A, Carson MJ, Morikis D, Wilson EH. SPARC coordinates extracellular matrix remodeling and efficient recruitment to and migration of antigen-specific T cells in the brain following infection. Sci Rep. 2021 02 25; 11(1):4549.

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Flores-Montoya MG, Bill CA, Vines CM, Sobin C. Early chronic low-level lead exposure reduced C-C chemokine receptor 7 in hippocampal microglia. Toxicol Lett. 2019 Oct 10; 314:106-116.

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Gaieb Z, Lo DD, Morikis D. Molecular Mechanism of Biased Ligand Conformational Changes in CC Chemokine Receptor 7. J Chem Inf Model. 2016 09 26; 56(9):1808-22.

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Shannon LA, McBurney TM, Wells MA, Roth ME, Calloway PA, Bill CA, Islam S, Vines CM. CCR7/CCL19 controls expression of EDG-1 in T cells. J Biol Chem. 2012 Apr 06; 287(15):11656-64.

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Shannon LA, Calloway PA, Welch TP, Vines CM. CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes. J Biol Chem. 2010 Dec 10; 285(50):38781-7.

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Noor S, Habashy AS, Nance JP, Clark RT, Nemati K, Carson MJ, Wilson EH. CCR7-dependent immunity during acute Toxoplasma gondii infection. Infect Immun. 2010 May; 78(5):2257-63.

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