Transforming Growth Factor beta3
"Transforming Growth Factor beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
| Descriptor ID |
D053782
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| MeSH Number(s) |
D12.644.276.374.687.300 D12.644.276.954.775.300 D12.776.467.374.687.300 D12.776.467.942.775.300 D23.529.942.775.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta3".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta3".
This graph shows the total number of publications written about "Transforming Growth Factor beta3" by people in this website by year, and whether "Transforming Growth Factor beta3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Transforming Growth Factor beta3" by people in Profiles.
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Chuang TD, Ton N, Rysling S, Quintanilla D, Boos D, Khorram O. Therapeutic effects of in?vivo administration of an inhibitor of tryptophan 2,3-dioxygenase (680c91) for the treatment of fibroids: a preclinical study. Fertil Steril. 2024 Apr; 121(4):669-678.
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Chuang TD, Munoz L, Quintanilla D, Boos D, Khorram O. Therapeutic Effects of Long-Term Administration of Tranilast in an Animal Model for the Treatment of Fibroids. Int J Mol Sci. 2023 Jun 21; 24(13).
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Chuang TD, Khorram O. Cross-talk between miR-29c and transforming growth factor-?3 is mediated by an epigenetic mechanism in leiomyoma. Fertil Steril. 2019 12; 112(6):1180-1189.
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Elliott B, Zackery DL, Eaton VA, Jones RT, Abebe F, Ragin CC, Khan SA. Ethnic differences in TGF?-signaling pathway may contribute to prostate cancer health disparity. Carcinogenesis. 2018 04 05; 39(4):546-555.
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Kimbrough-Allah MN, Millena AC, Khan SA. Differential role of PTEN in transforming growth factor ? (TGF-?) effects on proliferation and migration in prostate cancer cells. Prostate. 2018 04; 78(5):377-389.
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Halder SK, Goodwin JS, Al-Hendy A. 1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells. J Clin Endocrinol Metab. 2011 Apr; 96(4):E754-62.