Transforming Growth Factor beta2
"Transforming Growth Factor beta2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
| Descriptor ID |
D053781
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| MeSH Number(s) |
D12.644.276.374.687.200 D12.644.276.954.775.200 D12.776.467.374.687.200 D12.776.467.942.775.200 D23.529.374.687.200 D23.529.942.775.200
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| Concept/Terms |
Transforming Growth Factor beta2- Transforming Growth Factor beta2
- Glioblastoma-Derived T-Cell Suppressor Factor
- Glioblastoma Derived T Cell Suppressor Factor
- Cartilage-Inducing Factor-B
- Cartilage Inducing Factor B
- Polyergin
- TGF-beta2
- TGF-beta-2
- BSC-1 Cell Growth Inhibitor
- BSC 1 Cell Growth Inhibitor
- Suppressor Factor, T-Cell, Glioblastoma-Derived
|
Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta2".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta2".
This graph shows the total number of publications written about "Transforming Growth Factor beta2" by people in this website by year, and whether "Transforming Growth Factor beta2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta2" by people in Profiles.
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Betts-Obregon BS, Mondragon AA, Mendiola AS, LeBaron RG, Asmis R, Zou T, Gonzalez-Fernandez F, Tsin AT. TGF? induces BIGH3 expression and human retinal pericyte apoptosis: a novel pathway of diabetic retinopathy. Eye (Lond). 2016 Dec; 30(12):1639-1647.
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Sun Z, Schriewer J, Tang M, Marlin J, Taylor F, Shohet RV, Konorev EA. The TGF-? pathway mediates doxorubicin effects on cardiac endothelial cells. J Mol Cell Cardiol. 2016 Jan; 90:129-38.
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Ardila DC, Tamimi E, Danford FL, Haskett DG, Kellar RS, Doetschman T, Vande Geest JP. TGF?2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs. Biomaterials. 2015 Jan; 37:164-73.
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Vidro-Kotchan E, Yendluri BB, Le-Thai T, Tsin A. NBHA reduces acrolein-induced changes in ARPE-19 cells: possible involvement of TGF?. Curr Eye Res. 2011 Apr; 36(4):370-8.
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Sirad F, Hlaing S, Kovanecz I, Artaza JN, Garcia LA, Rajfer J, Ferrini MG. Sildenafil promotes smooth muscle preservation and ameliorates fibrosis through modulation of extracellular matrix and tissue growth factor gene expression after bilateral cavernosal nerve resection in the rat. J Sex Med. 2011 Apr; 8(4):1048-60.
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Vidro EK, Gee S, Unda R, Ma JX, Tsin A. Glucose and TGFbeta2 modulate the viability of cultured human retinal pericytes and their VEGF release. Curr Eye Res. 2008 Nov; 33(11):984-93.
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Nayyar T, Bruner-Tran KL, Piestrzeniewicz-Ulanska D, Osteen KG. Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis. Reprod Toxicol. 2007 Apr-May; 23(3):326-36.