"TRPV Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They contain a TRP domain (a five-turn amphipathic helix with an invariant TRYPTOPHAN) and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold.
| Descriptor ID |
D050916
|
| MeSH Number(s) |
D12.776.157.530.400.901.888
|
| Concept/Terms |
TRPV Cation Channels- TRPV Cation Channels
- Cation Channels, TRPV
- Channels, TRPV Cation
- Capsaicin Receptors
- Receptors, Capsaicin
- Vanilloid Receptors
- Receptors, Vanilloid
|
Below are MeSH descriptors whose meaning is more general than "TRPV Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPV Cation Channels".
This graph shows the total number of publications written about "TRPV Cation Channels" by people in this website by year, and whether "TRPV Cation Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPV Cation Channels" by people in Profiles.
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Baskaran P, Mohandass A, Gustafson N, Bennis J, Louis S, Alexander B, Nemenov MI, Thyagarajan B, Premkumar LS. Evaluation of a polymer-coated nanoparticle cream formulation of resiniferatoxin for the treatment of painful diabetic peripheral neuropathy. Pain. 2023 04 01; 164(4):782-790.
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Baskaran P, Nazminia K, Frantz J, O'Neal J, Thyagarajan B. Mice lacking endogenous TRPV1 express reduced levels of thermogenic proteins and are susceptible to diet-induced obesity and metabolic dysfunction. FEBS Lett. 2021 07; 595(13):1768-1781.
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Mohandass A, Surenkhuu B, Covington K, Baskaran P, Lehmann T, Thyagarajan B. Kainic Acid Activates TRPV1 via a Phospholipase C/PIP2-Dependent Mechanism in Vitro. ACS Chem Neurosci. 2020 10 07; 11(19):2999-3007.
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Pardo-Garc?a TR, Yusif-Rodriguez N, Yudowski G, Maldonado-Vlaar CS. Blockade of the endovanilloid receptor, TRPV1, and of the endocannabinoid enzyme, FAAH, within the nucleus accumbens shell elicits anxiolytic-like effects in male rats. Neurosci Lett. 2020 07 27; 732:135023.
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Horton JS, Shiraishi T, Alfulaij N, Small-Howard AL, Turner HC, Kurokawa T, Mori Y, Stokes AJ. "TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure". Channels (Austin). 2019 12; 13(1):1-16.
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Baskaran P, Covington K, Bennis J, Mohandass A, Lehmann T, Thyagarajan B. Binding Efficacy and Thermogenic Efficiency of Pungent and Nonpungent Analogs of Capsaicin. Molecules. 2018 Dec 04; 23(12).
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Krishnan V, Baskaran P, Thyagarajan B. Troglitazone activates TRPV1 and causes deacetylation of PPAR? in 3T3-L1 cells. Biochim Biophys Acta Mol Basis Dis. 2019 02 01; 1865(2):445-453.
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Ghoneum MH, Katano H, Agrawal S, Ganguly S, Agrawal A. Effect of Nanodiamond and Nanoplatinum Liquid, DPV576, on Human Primary Keratinocytes. J Biomed Nanotechnol. 2017 Jan; 13(1):110-16.
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Li J, Chen XL, Shaker A, Oshima T, Shan J, Miwa H, Feng C, Zhang J. Contribution of immunomodulators to gastroesophageal reflux disease and its complications: stromal cells, interleukin 4, and adiponectin. Ann N Y Acad Sci. 2016 09; 1380(1):183-194.
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Baskaran P, Krishnan V, Ren J, Thyagarajan B. Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel-dependent mechanisms. Br J Pharmacol. 2016 08; 173(15):2369-89.