Calcium Channels

"Calcium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.

Descriptor ID	D015220
MeSH Number(s)	D12.776.157.530.400.150 D12.776.543.550.450.150 D12.776.543.585.400.150
Concept/Terms	Calcium Channels Calcium Channels Ion Channel, Calcium Calcium Ion Channel Ion Channels, Calcium Calcium Ion Channels Calcium Channel Blocker Receptor VDCC Receptors, Calcium Channel Blocker Calcium Channel Antagonist Receptors Receptors, Calcium Channel Antagonist Calcium Channel Antagonist Receptor Voltage-Dependent Calcium Channels Calcium Channels, Voltage-Dependent Channels, Voltage-Dependent Calcium Voltage Dependent Calcium Channels Calcium Channel Calcium Channel Blocker Receptors

Below are MeSH descriptors whose meaning is more general than "Calcium Channels".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Channels [D12.776.157.530.400]
Calcium Channels [D12.776.157.530.400.150]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Ion Channels [D12.776.543.550.450]
Calcium Channels [D12.776.543.550.450.150]
Membrane Transport Proteins [D12.776.543.585]
Ion Channels [D12.776.543.585.400]
Calcium Channels [D12.776.543.585.400.150]

Below are MeSH descriptors whose meaning is related to "Calcium Channels".

Below are MeSH descriptors whose meaning is more specific than "Calcium Channels".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Calcium Channels" by people in this website by year, and whether "Calcium Channels" was a major or minor topic of these publications.

Bar chart showing 58 publications over 24 distinct years, with a maximum of 5 publications in 2000 and 2002 and 2006 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	2	1	3
2000	2	3	5
2001	1	0	1
2002	4	1	5
2003	2	2	4
2004	1	1	2
2005	1	0	1
2006	2	3	5
2007	1	1	2
2008	2	1	3
2010	1	4	5
2011	0	2	2
2012	0	1	1
2013	1	0	1
2014	1	0	1
2015	3	1	4
2016	1	0	1
2017	0	2	2
2018	0	1	1
2019	3	0	3
2020	1	1	2
2022	1	1	2
2024	1	0	1
2025	0	1	1

Below are the most recent publications written about "Calcium Channels" by people in Profiles.

Yamada A, Watanabe A, Nara A, Inokuma T, Asano M, Shinohara Y, Yamamoto T. Multiple Inhibitory Mechanisms of DS16570511 Targeting Mitochondrial Calcium Uptake: Insights from Biochemical Analysis of Rat Liver Mitochondria. Int J Mol Sci. 2025 Mar 16; 26(6).

View in: PubMed
Avery J, Leak-Johnson T, Francis SC. Association between MCU Gene Polymorphisms with Obesity: Findings from the All of Us Research Program. Genes (Basel). 2024 04 19; 15(4).

View in: PubMed
Gross S, Hooper R, Tomar D, Armstead AP, Shanas N, Mallu P, Joshi H, Ray S, Chong PL, Astsaturov I, Farma JM, Cai KQ, Chitrala KN, Elrod JW, Zaidi MR, Soboloff J. Suppression of Ca2+ signaling enhances melanoma progression. EMBO J. 2022 10 04; 41(19):e110046.

View in: PubMed
Watanabe A, Maeda K, Nara A, Hashida M, Ozono M, Nakao A, Yamada A, Shinohara Y, Yamamoto T. Quantitative analysis of mitochondrial calcium uniporter (MCU) and essential MCU regulator (EMRE) in mitochondria from mouse tissues and HeLa cells. FEBS Open Bio. 2022 04; 12(4):811-826.

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Nyarko-Danquah I, Pajarillo E, Digman A, Soliman KFA, Aschner M, Lee E. Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms. Molecules. 2020 Dec 12; 25(24).

View in: PubMed
Korolkova OY, Widatalla SE, Whalen DS, Nangami GN, Abimbola A, Williams SD, Beasley HK, Reisenbichler E, Washington MK, Ochieng J, Mayer IA, Lehmann BD, Sakwe AM. Reciprocal expression of Annexin A6 and RasGRF2 discriminates rapidly growing from invasive triple negative breast cancer subsets. PLoS One. 2020; 15(4):e0231711.

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Yamamoto T, Ozono M, Watanabe A, Maeda K, Nara A, Hashida M, Ido Y, Hiroshima Y, Yamada A, Terada H, Shinohara Y. Functional analysis of coiled-coil domains of MCU in mitochondrial calcium uptake. Biochim Biophys Acta Bioenerg. 2019 12 01; 1860(12):148061.

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Burks SR, Lorsung RM, Nagle ME, Tu TW, Frank JA. Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle. Theranostics. 2019; 9(19):5517-5531.

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Lange I, Koster J, Koomoa DT. Calcium signaling regulates fundamental processes involved in Neuroblastoma progression. Cell Calcium. 2019 09; 82:102052.

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de Pascual R, Baraibar AM, M?ndez-L?pez I, P?rez-Ciria M, Polo-Vaquero I, Gand?a L, Ohia SE, Garc?a AG, de Diego AMG. Hydrogen sulphide facilitates exocytosis by regulating the handling of intracellular calcium by chromaffin cells. Pflugers Arch. 2018 08; 470(8):1255-1270.

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