"Receptors, Dopamine D4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of dopamine D2 receptors that has high affinity for the antipsychotic CLOZAPINE.
| Descriptor ID |
D050638
|
| MeSH Number(s) |
D12.776.543.750.670.300.400.500.500 D12.776.543.750.695.150.400.500.750 D12.776.543.750.720.330.400.500.500
|
| Concept/Terms |
Receptors, Dopamine D4- Receptors, Dopamine D4
- D4 Receptors, Dopamine
- Dopamine D4 Receptor
- D4 Receptor, Dopamine
- Dopamine D4 Receptors
- Receptor, Dopamine D4
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Dopamine D4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Dopamine [D12.776.543.750.670.300.400]
- Receptors, Dopamine D2 [D12.776.543.750.670.300.400.500]
- Receptors, Dopamine D4 [D12.776.543.750.670.300.400.500.500]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Dopamine [D12.776.543.750.695.150.400]
- Receptors, Dopamine D2 [D12.776.543.750.695.150.400.500]
- Receptors, Dopamine D4 [D12.776.543.750.695.150.400.500.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Dopamine [D12.776.543.750.720.330.400]
- Receptors, Dopamine D2 [D12.776.543.750.720.330.400.500]
- Receptors, Dopamine D4 [D12.776.543.750.720.330.400.500.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Dopamine D4".
This graph shows the total number of publications written about "Receptors, Dopamine D4" by people in this website by year, and whether "Receptors, Dopamine D4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Dopamine D4" by people in Profiles.
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Yang JJ, Wang Z, Trucco EM, Buu A, Lin HC. Chronic pain and delinquency partially explain the effect of the DRD4 gene polymorphism on adult substance use. Am J Drug Alcohol Abuse. 2022 03 04; 48(2):235-244.
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Vancura P, Abdelhadi S, Csicsely E, Baba K, Tosini G, Iuvone PM, Spessert R. Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors. PLoS One. 2017; 12(10):e0187411.
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Vancura P, Wolloscheck T, Baba K, Tosini G, Iuvone PM, Spessert R. Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells. PLoS One. 2016; 11(10):e0164665.
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Trucco EM, Hicks BM, Villafuerte S, Nigg JT, Burmeister M, Zucker RA. Temperament and externalizing behavior as mediators of genetic risk on adolescent substance use. J Abnorm Psychol. 2016 05; 125(4):565-75.
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Villalba K, Devieux JG, Rosenberg R, Cadet JL. DRD2 and DRD4 genes related to cognitive deficits in HIV-infected adults who abuse alcohol. Behav Brain Funct. 2015 Aug 27; 11:25.
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Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Identification of a new selective dopamine D4 receptor ligand. Bioorg Med Chem. 2014 Jun 15; 22(12):3105-14.
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Sasaki JY, Kim HS, Mojaverian T, Kelley LD, Park IY, Janusonis S. Religion priming differentially increases prosocial behavior among variants of the dopamine D4 receptor (DRD4) gene. Soc Cogn Affect Neurosci. 2013 Feb; 8(2):209-15.
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Pozdeyev N, Tosini G, Li L, Ali F, Rozov S, Lee RH, Iuvone PM. Dopamine modulates diurnal and circadian rhythms of protein phosphorylation in photoreceptor cells of mouse retina. Eur J Neurosci. 2008 May; 27(10):2691-700.
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Lyles-Eggleston M, Altundas R, Xia J, Sikazwe DM, Fan P, Yang Q, Li S, Zhang W, Zhu X, Schmidt AW, Vanase-Frawley M, Shrihkande A, Villalobos A, Borne RF, Ablordeppey SY. Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species. J Med Chem. 2004 Jan 29; 47(3):497-508.
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Bookman EB, Taylor RE, Adams-Campbell L, Kittles RA. DRD4 promoter SNPs and gender effects on Extraversion in African Americans. Mol Psychiatry. 2002; 7(7):786-9.