Receptor, Serotonin, 5-HT1A
"Receptor, Serotonin, 5-HT1A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found distributed through the CENTRAL NERVOUS SYSTEM where they are involved in neuroendocrine regulation of ACTH secretion. The fact that this serotonin receptor subtype is particularly sensitive to SEROTONIN RECEPTOR AGONISTS such as BUSPIRONE suggests its role in the modulation of ANXIETY and DEPRESSION.
| Descriptor ID |
D044282
|
| MeSH Number(s) |
D12.776.543.750.670.800.100.100 D12.776.543.750.695.800.100.100 D12.776.543.750.720.850.100.100
|
| Concept/Terms |
Receptor, Serotonin, 5-HT1A- Receptor, Serotonin, 5-HT1A
- 5-HT1A Receptor
- 5 HT1A Receptor
- Receptor, 5-HT1A
- 5-Hydroxytryptamine 1A Receptor
- 1A Receptor, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1A Receptor
- 5-Hydroxytryptamine 1A Receptors
- 1A Receptors, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1A Receptors
- Receptors, 5-Hydroxytryptamine 1A
- Serotonin, 5-HT1a Receptor
- 5-HT1a Receptor Serotonin
- Receptor Serotonin, 5-HT1a
- Serotonin, 5 HT1a Receptor
- Serotonin 1A Receptor
- Receptor, Serotonin 1A
- Serotonin Receptor, 5-HT1A
- 5-HT1A Serotonin Receptor
- Receptor, 5-HT1A Serotonin
- Serotonin Receptor, 5 HT1A
- 5-HT(1A) Receptor
- Receptor, 5-Hydroxytryptamine 1A
- Receptor, 5 Hydroxytryptamine 1A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT1A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.670.800.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.670.800.100.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.695.800.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.695.800.100.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.850.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.720.850.100.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT1A".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT1A" by people in this website by year, and whether "Receptor, Serotonin, 5-HT1A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT1A" by people in Profiles.
-
Ofori E, Onyameh EK, Gonela UM, Voshavar C, Bricker B, Swanson TL, Eshleman AJ, Schmachtenberg JL, Bloom SH, Janowsky AJ, Ablordeppey SY. New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263. Eur J Med Chem. 2021 Mar 15; 214:113243.
-
Ofori E, Zhu XY, Etukala JR, Bricker BA, Ablordeppey SY. Synthesis and evaluation of the structural elements in alkylated tetrahydroisoquinolines for binding to CNS receptors. Bioorg Med Chem. 2016 11 15; 24(22):5730-5740.
-
Ofori E, Zhu XY, Etukala JR, Peprah K, Jordan KR, Adkins AA, Bricker BA, Kang HJ, Huang XP, Roth BL, Ablordeppey SY. Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands. Bioorg Med Chem. 2016 08 15; 24(16):3464-71.
-
Serafine KM, Rice KC, France CP. Directly Observable Behavioral Effects of Lorcaserin in Rats. J Pharmacol Exp Ther. 2015 Dec; 355(3):381-5.
-
Quadros IM, Hwa LS, Shimamoto A, Carlson J, DeBold JF, Miczek KA. Prevention of alcohol-heightened aggression by CRF-R1 antagonists in mice: critical role for DRN-PFC serotonin pathway. Neuropsychopharmacology. 2014 Nov; 39(12):2874-83.
-
Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Identification of a new selective dopamine D4 receptor ligand. Bioorg Med Chem. 2014 Jun 15; 22(12):3105-14.
-
Zhu XY, Etukala JR, Eyunni SV, Setola V, Roth BL, Ablordeppey SY. Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): a search for new dual-acting agents as potential antidepressants. Eur J Med Chem. 2012 Jul; 53:124-32.
-
Gdovin MJ, Zamora DA, Ravindran CR, Leiter JC. Serotonergic modulation of respiratory rhythmogenesis and central chemoreception. Ethn Dis. 2010; 20(1 Suppl 1):S1-39-44.
-
Kim HS, Sherman DK, Taylor SE, Sasaki JY, Chu TQ, Ryu C, Suh EM, Xu J. Culture, serotonin receptor polymorphism and locus of attention. Soc Cogn Affect Neurosci. 2010 Jun; 5(2-3):212-8.
-
Sanberg CD, Jones FL, Do VH, Dieguez D, Derrick BE. 5-HT1a receptor antagonists block perforant path-dentate LTP induced in novel, but not familiar, environments. Learn Mem. 2006 Jan-Feb; 13(1):52-62.