Pterocarpans

"Pterocarpans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of compounds which can be described as benzo-pyrano-furano-benzenes which can be formed from ISOFLAVONES by internal coupling of the B ring to the 4-ketone position. Members include medicarpin, phaseolin, and pisatin which are found in FABACEAE.

Descriptor ID	D036343
MeSH Number(s)	D03.383.663.283.266.450.400.687 D03.633.100.127.637 D03.633.100.150.266.450.400.687 D03.633.400.748
Concept/Terms	Pterocarpans Pterocarpans

Below are MeSH descriptors whose meaning is more general than "Pterocarpans".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyrans [D03.383.663]
Benzopyrans [D03.383.663.283]
Chromones [D03.383.663.283.266]
Flavonoids [D03.383.663.283.266.450]
Isoflavones [D03.383.663.283.266.450.400]
Pterocarpans [D03.383.663.283.266.450.400.687]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzofurans [D03.633.100.127]
Pterocarpans [D03.633.100.127.637]
Benzopyrans [D03.633.100.150]
Chromones [D03.633.100.150.266]
Flavonoids [D03.633.100.150.266.450]
Isoflavones [D03.633.100.150.266.450.400]
Pterocarpans [D03.633.100.150.266.450.400.687]
Heterocyclic Compounds, 4 or More Rings [D03.633.400]
Pterocarpans [D03.633.400.748]

Below are MeSH descriptors whose meaning is related to "Pterocarpans".

Below are MeSH descriptors whose meaning is more specific than "Pterocarpans".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pterocarpans" by people in this website by year, and whether "Pterocarpans" was a major or minor topic of these publications.

Bar chart showing 12 publications over 10 distinct years, with a maximum of 2 publications in 2015 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	0	1	1
2008	0	1	1
2009	1	0	1
2010	1	0	1
2011	1	0	1
2014	1	0	1
2015	2	0	2
2016	1	0	1
2017	2	0	2
2022	0	1	1

Below are the most recent publications written about "Pterocarpans" by people in Profiles.

Walker RR, Patel JR, Gupta A, Davidson AM, Williams CC, Payton-Stewart F, Bou? SM, Burow ME, Khupse R, Tilghman SL. Glyceollins Trigger Anti-Proliferative Effects in Hormone-Dependent Aromatase-Inhibitor-Resistant Breast Cancer Cells through the Induction of Apoptosis. Int J Mol Sci. 2022 Mar 07; 23(5).

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Bateman ME, Strong AL, Hunter RS, Bratton MR, Komati R, Sridhar J, Riley KE, Wang G, Hayes DJ, Boue SM, Burow ME, Bunnell BA. Osteoinductive effects of glyceollins on adult mesenchymal stromal/stem cells from adipose tissue and bone marrow. Phytomedicine. 2017 Apr 15; 27:39-51.

View in: PubMed
Selvam C, Jordan BC, Prakash S, Mutisya D, Thilagavathi R. Pterocarpan scaffold: A natural lead molecule with diverse pharmacological properties. Eur J Med Chem. 2017 Mar 10; 128:219-236.

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Chimezie C, Ewing A, Schexnayder C, Bratton M, Glotser E, Skripnikova E, S? P, Bou? S, Stratford RE. Glyceollin Effects on MRP2 and BCRP in Caco-2 Cells, and Implications for Metabolic and Transport Interactions. J Pharm Sci. 2016 Feb; 105(2):972-981.

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Carriere PP, Llopis SD, Naiki AC, Nguyen G, Phan T, Nguyen MM, Preyan LC, Yearby L, Pratt J, Burks H, Davenport IR, Nguyen TA, Parker-Lemieux K, Payton-Stewart F, Williams CC, Bou? SM, Burow ME, Collins-Burow B, Hilliard A, Davidson AM, Tilghman SL. Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1. Int J Environ Res Public Health. 2015 Dec 22; 13(1):ijerph13010010.

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Bratton MR, Martin EC, Elliott S, Rhodes LV, Collins-Burow BM, McLachlan JA, Wiese TE, Boue SM, Burow ME. Glyceollin, a novel regulator of mTOR/p70S6 in estrogen receptor positive breast cancer. J Steroid Biochem Mol Biol. 2015 Jun; 150:17-23.

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Chimezie C, Ewing AC, Quadri SS, Cole RB, Bou? SM, Omari CF, Bratton M, Glotser E, Skripnikova E, Townley I, Stratford RE. Glyceollin transport, metabolism, and effects on p-glycoprotein function in Caco-2 cells. J Med Food. 2014 Apr; 17(4):462-71.

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Khupse RS, Sarver JG, Trendel JA, Bearss NR, Reese MD, Wiese TE, Boue SM, Burow ME, Cleveland TE, Bhatnagar D, Erhardt PW. Biomimetic syntheses and antiproliferative activities of racemic, natural (-), and unnnatural (+) glyceollin I. J Med Chem. 2011 May 26; 54(10):3506-23.

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Payton-Stewart F, Khupse RS, Bou? SM, Elliott S, Zimmermann MC, Skripnikova EV, Ashe H, Tilghman SL, Beckman BS, Cleveland TE, McLachlan JA, Bhatnagar D, Wiese TE, Erhardt P, Burow ME. Glyceollin I enantiomers distinctly regulate ER-mediated gene expression. Steroids. 2010 Dec; 75(12):870-8.

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Zimmermann MC, Tilghman SL, Bou? SM, Salvo VA, Elliott S, Williams KY, Skripnikova EV, Ashe H, Payton-Stewart F, Vanhoy-Rhodes L, Fonseca JP, Corbitt C, Collins-Burow BM, Howell MH, Lacey M, Shih BY, Carter-Wientjes C, Cleveland TE, McLachlan JA, Wiese TE, Beckman BS, Burow ME. Glyceollin I, a novel antiestrogenic phytoalexin isolated from activated soy. J Pharmacol Exp Ther. 2010 Jan; 332(1):35-45.

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