"Perforant Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pathway of fibers that originates in the lateral part of the ENTORHINAL CORTEX, perforates the SUBICULUM of the HIPPOCAMPUS, and runs into the stratum moleculare of the hippocampus, where these fibers synapse with others that go to the DENTATE GYRUS where the pathway terminates. It is also known as the perforating fasciculus.
| Descriptor ID |
D019580
|
| MeSH Number(s) |
A08.186.211.464.730 A08.612.600
|
| Concept/Terms |
Perforant Pathway- Perforant Pathway
- Pathway, Perforant
- Pathways, Perforant
- Perforant Pathways
- Perforant Path
- Path, Perforant
- Paths, Perforant
- Perforant Paths
- Perforating Fasciculus
- Fasciculus, Perforating
|
Below are MeSH descriptors whose meaning is more general than "Perforant Pathway".
Below are MeSH descriptors whose meaning is more specific than "Perforant Pathway".
This graph shows the total number of publications written about "Perforant Pathway" by people in this website by year, and whether "Perforant Pathway" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Perforant Pathway" by people in Profiles.
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Gonzalez J, Villarreal DM, Morales IS, Derrick BE. Long-term Potentiation at Temporoammonic Path-CA1 Synapses in Freely Moving Rats. Front Neural Circuits. 2016; 10:2.
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Dao AT, Zagaar MA, Alkadhi KA. Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer's Disease. Mol Neurobiol. 2015 Dec; 52(3):1067-1076.
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Gonzalez J, Morales IS, Villarreal DM, Derrick BE. Low-frequency stimulation induces long-term depression and slow onset long-term potentiation at perforant path-dentate gyrus synapses in vivo. J Neurophysiol. 2014 Mar; 111(6):1259-73.
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Martinez CO, Do VH, Derrick BE. Endogenous opioid peptides contribute to associative LTP in the hippocampal CA3 region. Neurobiol Learn Mem. 2011 Sep; 96(2):207-17.
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Villarreal DM, Derrick B, Vathy I. Prenatal morphine exposure attenuates the maintenance of late LTP in lateral perforant path projections to the dentate gyrus and the CA3 region in vivo. J Neurophysiol. 2008 Mar; 99(3):1235-42.
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Villarreal DM, Gross AL, Derrick BE. Modulation of CA3 afferent inputs by novelty and theta rhythm. J Neurosci. 2007 Dec 05; 27(49):13457-67.
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Pastalkova E, Serrano P, Pinkhasova D, Wallace E, Fenton AA, Sacktor TC. Storage of spatial information by the maintenance mechanism of LTP. Science. 2006 Aug 25; 313(5790):1141-4.
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Sanberg CD, Jones FL, Do VH, Dieguez D, Derrick BE. 5-HT1a receptor antagonists block perforant path-dentate LTP induced in novel, but not familiar, environments. Learn Mem. 2006 Jan-Feb; 13(1):52-62.
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Kosub KA, Do VH, Derrick BE. NMDA receptor antagonists block heterosynaptic long-term depression (LTD) but not long-term potentiation (LTP) in the CA3 region following lateral perforant path stimulation. Neurosci Lett. 2005 Feb 01; 374(1):29-34.
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Davis CD, Jones FL, Derrick BE. Novel environments enhance the induction and maintenance of long-term potentiation in the dentate gyrus. J Neurosci. 2004 Jul 21; 24(29):6497-506.