Long-Term Synaptic Depression
"Long-Term Synaptic Depression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
| Descriptor ID |
D036881
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| MeSH Number(s) |
G11.561.638.355
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| Concept/Terms |
Long-Term Synaptic Depression- Long-Term Synaptic Depression
- Long Term Synaptic Depression
- Synaptic Depression, Long-Term
- Long-Term Depression, Physiological
- Depression, Physiological Long-Term
- Depressions, Physiological Long-Term
- Long Term Depression, Physiological
- Long-Term Depressions, Physiological
- Physiological Long-Term Depression
- Physiological Long-Term Depressions
- Long-Term Depression, Neurophysiological
- Depression, Neurophysiological Long-Term
- Depressions, Neurophysiological Long-Term
- Long Term Depression, Neurophysiological
- Long-Term Depressions, Neurophysiological
- Neurophysiological Long-Term Depression
- Neurophysiological Long-Term Depressions
- Long-Term Depression, Physiologic
- Long Term Depression, Physiologic
- Physiologic Long-Term Depression
- Long-Term Depression, Neurophysiologic
- Long Term Depression, Neurophysiologic
- Neurophysiologic Long-Term Depression
Depotentiation- Depotentiation
- Homosynaptic Depression
- Depression, Homosynaptic
|
Below are MeSH descriptors whose meaning is more general than "Long-Term Synaptic Depression".
Below are MeSH descriptors whose meaning is more specific than "Long-Term Synaptic Depression".
This graph shows the total number of publications written about "Long-Term Synaptic Depression" by people in this website by year, and whether "Long-Term Synaptic Depression" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Long-Term Synaptic Depression" by people in Profiles.
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Barylko B, Wilkerson JR, Cavalier SH, Binns DD, James NG, Jameson DM, Huber KM, Albanesi JP. Palmitoylation and Membrane Binding of Arc/Arg3.1: A Potential Role in Synaptic Depression. Biochemistry. 2018 02 06; 57(5):520-524.
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Yang Z, Santamaria F. Purkinje cell intrinsic excitability increases after synaptic long term depression. J Neurophysiol. 2016 09 01; 116(3):1208-17.
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Mizui T, Ishikawa Y, Kumanogoh H, Kojima M. Neurobiological actions by three distinct subtypes of brain-derived neurotrophic factor: Multi-ligand model of growth factor signaling. Pharmacol Res. 2016 Mar; 105:93-8.
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Mizui T, Ishikawa Y, Kumanogoh H, Lume M, Matsumoto T, Hara T, Yamawaki S, Takahashi M, Shiosaka S, Itami C, Uegaki K, Saarma M, Kojima M. BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met. Proc Natl Acad Sci U S A. 2015 Jun 09; 112(23):E3067-74.
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Gonzalez J, Morales IS, Villarreal DM, Derrick BE. Low-frequency stimulation induces long-term depression and slow onset long-term potentiation at perforant path-dentate gyrus synapses in vivo. J Neurophysiol. 2014 Mar; 111(6):1259-73.
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Nagura H, Ishikawa Y, Kobayashi K, Takao K, Tanaka T, Nishikawa K, Tamura H, Shiosaka S, Suzuki H, Miyakawa T, Fujiyoshi Y, Doi T. Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice. Mol Brain. 2012 Dec 26; 5:43.
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Ishikawa Y, Tamura H, Shiosaka S. Diversity of neuropsin (KLK8)-dependent synaptic associativity in the hippocampal pyramidal neuron. J Physiol. 2011 Jul 15; 589(Pt 14):3559-73.
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Coleman WL, Bykhovskaia M. Cooperative regulation of neurotransmitter release by Rab3a and synapsin II. Mol Cell Neurosci. 2010 Jun; 44(2):190-200.
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Tanaka K, Khiroug L, Santamaria F, Doi T, Ogasawara H, Ellis-Davies GC, Kawato M, Augustine GJ. Ca2+ requirements for cerebellar long-term synaptic depression: role for a postsynaptic leaky integrator. Neuron. 2007 Jun 07; 54(5):787-800.
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Wilson CJ. Striatal D2 receptors and LTD: yes, but not where you thought they were. Neuron. 2006 May 04; 50(3):347-8.