Iron Overload

"Iron Overload" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)

Descriptor ID	D019190
MeSH Number(s)	C18.452.565.500
Concept/Terms	Iron Overload Iron Overload Overload, Iron

Below are MeSH descriptors whose meaning is more general than "Iron Overload".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Iron Metabolism Disorders [C18.452.565]
Iron Overload [C18.452.565.500]

Below are MeSH descriptors whose meaning is related to "Iron Overload".

Below are MeSH descriptors whose meaning is more specific than "Iron Overload".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Iron Overload" by people in this website by year, and whether "Iron Overload" was a major or minor topic of these publications.

Bar chart showing 10 publications over 9 distinct years, with a maximum of 2 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2003	1	0	1
2009	1	0	1
2011	0	1	1
2014	0	1	1
2016	2	0	2
2022	1	0	1
2024	1	0	1
2025	0	1	1

Below are the most recent publications written about "Iron Overload" by people in Profiles.

Garcia-Baez J, Chaves-Negr?n I, Javadov S, Bazil JN, Chapa-Dubocq XR. Developing a physiologically relevant cell model of ferroptosis in cardiomyocytes. Free Radic Biol Med. 2025 Jun; 233:330-339.

View in: PubMed
Yuan Y, He Q, Yang X, Flores JJ, Huang L, Luo X, Zhang X, Zhang Z, Li R, Gu L, Dong S, Zhu S, Yi K, Han M, Wu L, Zhou Y, Zhang JH, Xie Z, Tang J. Mitochondrial ferritin upregulation reduced oxidative stress and blood-brain-barrier disruption by maintaining cellular iron homeostasis in a neonatal rat model of germinal matrix hemorrhage. Exp Neurol. 2024 Apr; 374:114703.

View in: PubMed
Sullivan KE, Lavin SR, Livingston S, Knutson M, Valdes EV, Warren LK. Safety and efficacy of a novel iron chelator (HBED; (N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid)) in equine (Equus caballus) as a model for black rhinoceros (Diceros bicornis). J Anim Physiol Anim Nutr (Berl). 2022 Sep; 106(5):1107-1117.

View in: PubMed
Hofer T, Perry G. Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis? J Trace Elem Med Biol. 2016 Dec; 38:1-9.

View in: PubMed
Tolouian R, Mulla ZD, Diaz J, Aguila J, Ramos-Duran L. Liver and Cardiac Iron Deposition in Patients on Maintenance Hemodialysis by Magnetic Resonance Imaging T2. Iran J Kidney Dis. 2016 Mar; 10(2):68-74.

View in: PubMed
Nouraie M, Gordeuk VR. Blood transfusion and 30-day readmission rate in adult patients hospitalized with sickle cell disease crisis. Transfusion. 2015 Oct; 55(10):2331-8.

View in: PubMed
Wang X, Mendelsohn L, Rogers H, Leitman S, Raghavachari N, Yang Y, Yau YY, Tallack M, Perkins A, Taylor JG, Noguchi CT, Kato GJ. Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Kr?ppel-like factor. Blood. 2014 Aug 07; 124(6):946-54.

View in: PubMed
McLaren CE, McLachlan S, Garner CP, Vulpe CD, Gordeuk VR, Eckfeldt JH, Adams PC, Acton RT, Murray JA, Leiendecker-Foster C, Snively BM, Barcellos LF, Cook JD, McLaren GD. Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations. PLoS One. 2012; 7(6):e38339.

View in: PubMed
Darbari DS, Onyekwere O, Nouraie M, Minniti CP, Luchtman-Jones L, Rana S, Sable C, Ensing G, Dham N, Campbell A, Arteta M, Gladwin MT, Castro O, Taylor JG, Kato GJ, Gordeuk V. Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia. J Pediatr. 2012 Feb; 160(2):286-90.

View in: PubMed
McLaren CE, Garner CP, Constantine CC, McLachlan S, Vulpe CD, Snively BM, Gordeuk VR, Nickerson DA, Cook JD, Leiendecker-Foster C, Beckman KB, Eckfeldt JH, Barcellos LF, Murray JA, Adams PC, Acton RT, Killeen AA, McLaren GD. Genome-wide association study identifies genetic loci associated with iron deficiency. PLoS One. 2011 Mar 31; 6(3):e17390.

View in: PubMed

People

Explore

Similar Concepts

Top Journals