Ribonucleoprotein, U2 Small Nuclear
"Ribonucleoprotein, U2 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U2 snRNP along with other small nuclear ribonucleoproteins (U1, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U2 snRNA forms base pairs with conserved sequence motifs at the branch point, which associates with a heat- and RNAase-sensitive factor in an early step of splicing.
| Descriptor ID |
D017413
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| MeSH Number(s) |
D12.776.157.725.500.875.605 D12.776.157.725.829.344 D12.776.664.962.500.875.605 D12.776.664.962.829.344
|
| Concept/Terms |
Ribonucleoprotein, U2 Small Nuclear- Ribonucleoprotein, U2 Small Nuclear
- U2 Small Nuclear Ribonucleoproteins
- Ribonucleoproteins, Small, U2
- Small Nuclear Ribonucleoproteins, U2
- U2 snRNP
|
Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U2 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U2 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U2 Small Nuclear" by people in this website by year, and whether "Ribonucleoprotein, U2 Small Nuclear" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ribonucleoprotein, U2 Small Nuclear" by people in Profiles.
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Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, Xing Z, Fan R, Zhang QC, Shi Y. Structural insights into branch site proofreading by human spliceosome. Nat Struct Mol Biol. 2024 May; 31(5):835-845.
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Perea W, Schroeder KT, Bryant AN, Greenbaum NL. Interaction between the Spliceosomal Pre-mRNA Branch Site and U2 snRNP Protein p14. Biochemistry. 2016 Feb 02; 55(4):629-32.