Sequence Alignment

"Sequence Alignment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.

Descriptor ID	D016415
MeSH Number(s)	E05.393.751
Concept/Terms	Sequence Alignment Sequence Alignment Alignment, Sequence Alignments, Sequence Sequence Alignments Determination, Sequence Homology Determination, Sequence Homology Determinations, Sequence Homology Sequence Homology Determinations Sequence Homology Determination

Below are MeSH descriptors whose meaning is more general than "Sequence Alignment".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Sequence Alignment [E05.393.751]

Below are MeSH descriptors whose meaning is more specific than "Sequence Alignment".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sequence Alignment" by people in this website by year, and whether "Sequence Alignment" was a major or minor topic of these publications.

Bar chart showing 234 publications over 28 distinct years, with a maximum of 21 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
1997	0	5	5
1998	0	4	4
1999	0	6	6
2000	0	12	12
2001	0	7	7
2002	0	7	7
2003	1	17	18
2004	2	14	16
2005	2	19	21
2006	3	13	16
2007	1	10	11
2008	0	10	10
2009	0	14	14
2010	1	10	11
2011	0	10	10
2012	1	10	11
2013	0	10	10
2014	0	9	9
2015	0	8	8
2016	0	9	9
2017	0	5	5
2018	0	5	5
2019	0	1	1
2020	0	1	1
2021	0	3	3
2023	0	1	1
2025	0	1	1

Below are the most recent publications written about "Sequence Alignment" by people in Profiles.

Anthony M, Xie Y, O'Neil JN, Teng S. Structural Analysis of Missense Mutations on the Stability of APOE3 and APOE4. Genes (Basel). 2025 Dec 16; 16(12).

View in: PubMed
Nakatsu K, Jijiwa M, Khadka V, Nasu M, Deng Y. sRNAfrag: a pipeline and suite of tools to analyze fragmentation in small RNA sequencing data. Brief Bioinform. 2023 11 22; 25(1).

View in: PubMed
Foox J, Nordlund J, Lalancette C, Gong T, Lacey M, Lent S, Langhorst BW, Ponnaluri VKC, Williams L, Padmanabhan KR, Cavalcante R, Lundmark A, Butler D, Mozsary C, Gurvitch J, Greally JM, Suzuki M, Menor M, Nasu M, Alonso A, Sheridan C, Scherer A, Bruinsma S, Golda G, Muszynska A, Labaj PP, Campbell MA, Wos F, Raine A, Liljedahl U, Axelsson T, Wang C, Chen Z, Yang Z, Li J, Yang X, Wang H, Melnick A, Guo S, Blume A, Franke V, Ibanez de Caceres I, Rodriguez-Antolin C, Rosas R, Davis JW, Ishii J, Megherbi DB, Xiao W, Liao W, Xu J, Hong H, Ning B, Tong W, Akalin A, Wang Y, Deng Y, Mason CE. The SEQC2 epigenomics quality control (EpiQC) study. Genome Biol. 2021 12 06; 22(1):332.

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Toro TB, Swanier JS, Bezue JA, Broussard CG, Watt TJ. Lysine Deacetylase Substrate Selectivity: A Dynamic Ionic Interaction Specific to KDAC8. Biochemistry. 2021 08 24; 60(33):2524-2536.

View in: PubMed
Chen X, Liao S, Makaros Y, Guo Q, Zhu Z, Krizelman R, Dahan K, Tu X, Yao X, Koren I, Xu C. Molecular basis for arginine C-terminal degron recognition by Cul2FEM1 E3 ligase. Nat Chem Biol. 2021 03; 17(3):254-262.

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Tessler M, Gaffney JP, Oliveira AG, Guarnaccia A, Dobi KC, Gujarati NA, Galbraith M, Mirza JD, Sparks JS, Pieribone VA, Wood RJ, Gruber DF. A putative chordate luciferase from a cosmopolitan tunicate indicates convergent bioluminescence evolution across phyla. Sci Rep. 2020 10 20; 10(1):17724.

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Case BC, Hartley S, Osuga M, Jeruzalmi D, Hingorani MM. The ATPase mechanism of UvrA2 reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair. Nucleic Acids Res. 2019 05 07; 47(8):4136-4152.

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Ullah K, Zubia E, Narayan M, Yang J, Xu G. Diverse roles of the E2/E3 hybrid enzyme UBE2O in the regulation of protein ubiquitination, cellular functions, and disease onset. FEBS J. 2019 06; 286(11):2018-2034.

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Valdez-Lopez JC, Donohue MW, Bok MJ, Wolf J, Cronin TW, Porter ML. Sequence, Structure, and Expression of Opsins in the Monochromatic Stomatopod Squilla empusa. Integr Comp Biol. 2018 09 01; 58(3):386-397.

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Hern?ndez F, Cuadros R, Oll? I, Garc?a C, Ferrer I, Perry G, Avila J. Differences in structure and function between human and murine tau. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2024-2030.

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