Open Reading Frames

"Open Reading Frames" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).

Descriptor ID	D016366
MeSH Number(s)	G05.360.335.760.640 G05.360.340.024.340.137.650
Concept/Terms	Open Reading Frames Open Reading Frames Frame, Open Reading Frames, Open Reading Open Reading Frame Reading Frame, Open Reading Frames, Open ORFs Protein Coding Region Coding Region, Protein Coding Regions, Protein Protein Coding Regions Region, Protein Coding Regions, Protein Coding Unassigned Reading Frames Unassigned Reading Frames Frame, Unassigned Reading Frames, Unassigned Reading Reading Frame, Unassigned Reading Frames, Unassigned Unassigned Reading Frame Unidentified Reading Frame Frame, Unidentified Reading Frames, Unidentified Reading Reading Frame, Unidentified Reading Frames, Unidentified Unidentified Reading Frames

Below are MeSH descriptors whose meaning is more general than "Open Reading Frames".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genetic Code [G05.360.335]
Reading Frames [G05.360.335.760]
Open Reading Frames [G05.360.335.760.640]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Gene Components [G05.360.340.024.340.137]
Open Reading Frames [G05.360.340.024.340.137.650]

Below are MeSH descriptors whose meaning is related to "Open Reading Frames".

Below are MeSH descriptors whose meaning is more specific than "Open Reading Frames".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Open Reading Frames" by people in this website by year, and whether "Open Reading Frames" was a major or minor topic of these publications.

Bar chart showing 70 publications over 27 distinct years, with a maximum of 9 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	0	1	1
1999	2	1	3
2000	0	3	3
2001	0	6	6
2002	0	2	2
2003	0	3	3
2004	2	7	9
2005	0	3	3
2006	1	2	3
2007	1	3	4
2008	1	3	4
2009	0	3	3
2010	0	1	1
2011	0	2	2
2012	1	2	3
2013	1	2	3
2014	0	3	3
2015	1	0	1
2016	0	1	1
2017	0	2	2
2018	0	2	2
2019	0	1	1
2020	0	1	1
2021	1	0	1
2023	0	2	2
2025	0	1	1

Below are the most recent publications written about "Open Reading Frames" by people in Profiles.

Nguyen TD, Wang J, Lam MT, McFerrin H, O'Grady TM, Roberts C, Van Otterloo N, Nguyen TT, Baddoo M, Wyczechowska D, Morales M, Dong Y, Flemington EK. Comprehensive resolution and classification of the Epstein Barr virus transcriptome. Nat Commun. 2025 Jul 10; 16(1):6381.

View in: PubMed
Xiang Y, Huang W, Tan L, Chen T, He Y, Irving PS, Weeks KM, Zhang QC, Dong X. Pervasive downstream RNA hairpins dynamically dictate start-codon selection. Nature. 2023 09; 621(7978):423-430.

View in: PubMed
Bykova A, Saura A, Glazko GV, Roche-Lima A, Yurchenko V, Rogozin IB. The 29-nucleotide deletion in SARS-CoV: truncated versions of ORF8 are under purifying selection. BMC Genomics. 2023 Jul 10; 24(1):387.

View in: PubMed
Blythe MJ, Kocer A, Rubio-Roldan A, Giles T, Abakir A, Ialy-Radio C, Wheldon LM, Bereshchenko O, Bruscoli S, Kondrashov A, Drevet JR, Emes RD, Johnson AD, McCarrey JR, Gackowski D, Olinski R, Cocquet J, Garcia-Perez JL, Ruzov A. LINE-1 transcription in round spermatids is associated with accretion of 5-carboxylcytosine in their open reading frames. Commun Biol. 2021 06 07; 4(1):691.

View in: PubMed
Ju X, Xiang G, Gong M, Yang R, Qin J, Li Y, Nan Y, Yang Y, Zhang QC, Ding Q. Identification of functional cis-acting RNA elements in the hepatitis E virus genome required for viral replication. PLoS Pathog. 2020 05; 16(5):e1008488.

View in: PubMed
Zhang B, Han Z, Kumar S, Gupta M, Su WW. Intein-ubiquitin chimeric domain for coordinated protein coexpression. J Biotechnol. 2019 Oct 10; 304:38-43.

View in: PubMed
Yang H, Zhang JE, Xia J, Yang J, Guo J, Deng Z, Luo M. Comparative Characterization of the Complete Mitochondrial Genomes of the Three Apple Snails (Gastropoda: Ampullariidae) and the Phylogenetic Analyses. Int J Mol Sci. 2018 Nov 19; 19(11).

View in: PubMed
Yang H, Xia J, Zhang JE, Yang J, Zhao H, Wang Q, Sun J, Xue H, Wu Y, Chen J, Huang J, Liu L. Characterization of the Complete Mitochondrial Genome Sequences of Three Croakers (Perciformes, Sciaenidae) and Novel Insights into the Phylogenetics. Int J Mol Sci. 2018 Jun 12; 19(6).

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Zhao ZM, Campbell MC, Li N, Lee DSW, Zhang Z, Townsend JP. Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence. Mol Biol Evol. 2017 Nov 01; 34(11):3006-3022.

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Munoz S, Guerrero FD, Kellogg A, Heekin AM, Leung MY. Bioinformatic prediction of G protein-coupled receptor encoding sequences from the transcriptome of the foreleg, including the Haller's organ, of the cattle tick, Rhipicephalus australis. PLoS One. 2017; 12(2):e0172326.

View in: PubMed

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