"Dizocilpine Maleate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects.
| Descriptor ID |
D016291
|
| MeSH Number(s) |
D02.455.426.559.847.181.384.380 D04.615.181.384.380
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dizocilpine Maleate".
Below are MeSH descriptors whose meaning is more specific than "Dizocilpine Maleate".
This graph shows the total number of publications written about "Dizocilpine Maleate" by people in this website by year, and whether "Dizocilpine Maleate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 2 | 3 |
| 1997 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 2 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Dizocilpine Maleate" by people in Profiles.
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Nygard SK, Klambatsen A, Balouch B, Quinones-Jenab V, Jenab S. NMDAR dependent intracellular responses associated with cocaine conditioned place preference behavior. Behav Brain Res. 2017 01 15; 317:218-225.
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Gonzalez J, Villarreal DM, Morales IS, Derrick BE. Long-term Potentiation at Temporoammonic Path-CA1 Synapses in Freely Moving Rats. Front Neural Circuits. 2016; 10:2.
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Pitts MW, Kremer PM, Hashimoto AC, Torres DJ, Byrns CN, Williams CS, Berry MJ. Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease. J Neurosci. 2015 Nov 18; 35(46):15326-38.
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Berger ML, Maciejewska D, Vanden Eynde JJ, Mottamal M, Zabinski J, Kazmierczak P, Rezler M, Jarak I, Piantanida I, Karminski-Zamola G, Mayence A, Rebernik P, Kumar A, Ismail MA, Boykin DW, Huang TL. Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors. Bioorg Med Chem. 2015 Aug 01; 23(15):4489-4500.
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Sun WL, Zhou L, Quinones-Jenab V, Jenab S. Cocaine effects on dopamine and NMDA receptors interactions in the striatum of Fischer rats. Brain Res Bull. 2009 Dec 16; 80(6):377-81.
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Rasmussen BA, Perry DC, O'Neil J, Manaye KF, Tizabi Y. Effects of nicotine on sensorimotor gating impairment induced by long-term treatment with neurotoxic NMDA antagonism. Neurotox Res. 2008 May-Jun; 13(3-4):151-61.
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Li Y, Xu Z, Ford GD, Croslan DR, Cairobe T, Li Z, Ford BD. Neuroprotection by neuregulin-1 in a rat model of permanent focal cerebral ischemia. Brain Res. 2007 Dec 12; 1184:277-83.
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Simon R, Henshall D, Stoehr S, Meller R. Endogenous mechanisms of neuroprotection. Epilepsia. 2007; 48 Suppl 8:72-3.
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Ortiz JG, Rassi N, Maldonado PM, Gonz?lez-Cabrera S, Ramos I. Commercial valerian interactions with [3H]Flunitrazepam and [3H]MK-801 binding to rat synaptic membranes. Phytother Res. 2006 Sep; 20(9):794-8.
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Lee E, Williams Z, Goodman CB, Oriaku ET, Harris C, Thomas M, Soliman KF. Effects of NMDA receptor inhibition by phencyclidine on the neuronal differentiation of PC12 cells. Neurotoxicology. 2006 Jul; 27(4):558-66.