"Amitriptyline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
| Descriptor ID |
D000639
|
| MeSH Number(s) |
D02.455.426.559.847.181.384.100 D04.615.181.384.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Amitriptyline".
Below are MeSH descriptors whose meaning is more specific than "Amitriptyline".
This graph shows the total number of publications written about "Amitriptyline" by people in this website by year, and whether "Amitriptyline" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amitriptyline" by people in Profiles.
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Pramar YV, Mandal TK, Bostanian LA, Kader C, Morris TC, Graves RA. Physicochemical and Microbiological Stability of Amitriptyline Hydrochloride Oral Liquid Dosage Forms in PCCA Base, SuspendIt. Int J Pharm Compd. 2022 Jul-Aug; 26(4):342-351.
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Suzuki T, Kurita H, Hori T, Sasaki M, Baba A, Shiraishi H, Piletz JE. The Pisa syndrome (pleurothotonus) during antidepressant therapy. Biol Psychiatry. 1997 Jan 15; 41(2):234-6.
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Yakubu MA, Deighton NM, Hamilton CA, Reid JL. Differences in the regulation of [3H]idazoxan and [3H]yohimbine binding sites in the rabbit. Eur J Pharmacol. 1990 Feb 13; 176(3):305-11.
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Paykel ES, Mueller PS, De la Vergne PM. Amitriptyline, weight gain and carbohydrate craving: a side effect. Br J Psychiatry. 1973 Nov; 123(576):501-7.
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Heninger GR, Mueller PS. Carbohydrate metabolism in mania before and after lithium carbonate treatment. Arch Gen Psychiatry. 1970 Oct; 23(4):310-9.
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Mueller PS, Heninger GR, McDonald RK. Insulin tolerance test in depression. Arch Gen Psychiatry. 1969 Nov; 21(5):587-94.
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Mueller PS, Heninger GR, McDonald RK. Intravenous glucose tolerance test in depression. Arch Gen Psychiatry. 1969 Oct; 21(4):470-7.