"Retinaldehyde" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration.
Descriptor ID |
D012172
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MeSH Number(s) |
D02.047.850 D02.455.326.271.665.202.495.690 D02.455.426.392.368.367.379.249.700.690 D02.455.849.131.495.690 D23.767.261.700.690
|
Concept/Terms |
Retinaldehyde- Retinaldehyde
- Vitamin A Aldehyde
- Aldehyde, Vitamin A
- Retinene
- Axerophthal
- Retinal
|
Below are MeSH descriptors whose meaning is more general than "Retinaldehyde".
Below are MeSH descriptors whose meaning is more specific than "Retinaldehyde".
This graph shows the total number of publications written about "Retinaldehyde" by people in this website by year, and whether "Retinaldehyde" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1998 | 0 | 1 | 1 |
1999 | 1 | 0 | 1 |
2000 | 0 | 1 | 1 |
2006 | 0 | 2 | 2 |
2012 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinaldehyde" by people in Profiles.
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Zueva L, Golubeva T, Korneeva E, Resto O, Inyushin M, Khmelinskii I, Makarov V. Quantum mechanism of light energy propagation through an avian retina. J Photochem Photobiol B. 2019 Aug; 197:111543.
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Gonzalez-Fernandez F, Betts-Obregon B, Yust B, Mimun J, Sung D, Sardar D, Tsin AT. Interphotoreceptor retinoid-binding protein protects retinoids from photodegradation. Photochem Photobiol. 2015 Mar-Apr; 91(2):371-8.
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Cheung LK, Eaton A. Age-related macular degeneration. Pharmacotherapy. 2013 Aug; 33(8):838-55.
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Betts BS, Obregon I, Tsin AT. Cultured M?ller cells from mammals can synthesize and accumulate retinyl esters. Exp Eye Res. 2012 Aug; 101:56-9.
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Villazana-Espinoza ET, Hatch AL, Tsin AT. Effect of light exposure on the accumulation and depletion of retinyl ester in the chicken retina. Exp Eye Res. 2006 Oct; 83(4):871-6.
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Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006; 1(4):327-48.
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Renthal R, Gracia N, Regalado R. Water and carboxyl group environments in the dehydration blueshift of bacteriorhodopsin. Photochem Photobiol. 2000 Nov; 72(5):714-8.
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Renthal R, Alaniz C. Conformational change in bacterio-opsin on binding to retinal. Biophys Chem. 1999 Apr 19; 78(3):241-5.
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Mata NL, Tsin AT. Distribution of 11-cis LRAT, 11-cis RD and 11-cis REH in bovine retinal pigment epithelium membranes. Biochim Biophys Acta. 1998 Oct 02; 1394(1):16-22.
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Renthal R, McMillan K, Guerra L, Garcia MN, Rangel R, Jen CM. Long-range effects on the retinal chromophore of bacteriorhodopsin caused by surface carboxyl group modification. Biochemistry. 1995 Jun 20; 34(24):7869-78.