"Fenretinide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
| Descriptor ID |
D017313
|
| MeSH Number(s) |
D02.455.326.271.665.202.495.270 D02.455.426.392.368.367.379.249.700.270 D02.455.849.131.495.270 D23.767.261.700.270
|
| Concept/Terms |
Fenretinide- Fenretinide
- N-(4-Hydroxyphenyl)-trans-Retinamide
- Fenretinimide
- N-(4-Hydroxyphenyl)retinamide
- 4-HPR
- 4-Hydroxyphenylretinamide
- 4 Hydroxyphenylretinamide
|
Below are MeSH descriptors whose meaning is more general than "Fenretinide".
Below are MeSH descriptors whose meaning is more specific than "Fenretinide".
This graph shows the total number of publications written about "Fenretinide" by people in this website by year, and whether "Fenretinide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fenretinide" by people in Profiles.
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Graves RA, Ledet GA, Glotser EY, Mitchner DM, Bostanian LA, Mandal TK. Formulation and evaluation of biodegradable nanoparticles for the oral delivery of fenretinide. Eur J Pharm Sci. 2015 Aug 30; 76:1-9.
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Ledet GA, Graves RA, Glotser EY, Mandal TK, Bostanian LA. Preparation and in vitro evaluation of hydrophilic fenretinide nanoparticles. Int J Pharm. 2015 Feb 20; 479(2):329-37.
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Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products. Cancer Res. 2005 Oct 15; 65(20):9555-65.
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Herbert BS, Sanders BG, Kline K. N-(4-hydroxyphenyl)retinamide activation of transforming growth factor-beta and induction of apoptosis in human breast cancer cells. Nutr Cancer. 1999; 34(2):121-32.