"Propylthiouracil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
| Descriptor ID |
D011441
|
| MeSH Number(s) |
D03.383.742.698.875.842.708
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Propylthiouracil".
Below are MeSH descriptors whose meaning is more specific than "Propylthiouracil".
This graph shows the total number of publications written about "Propylthiouracil" by people in this website by year, and whether "Propylthiouracil" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Propylthiouracil" by people in Profiles.
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Chen MC, Wang SW, Kan SF, Tsai SC, Wu YC, Wang PS. Stimulatory effects of propylthiouracil on pregnenolone production through upregulation of steroidogenic acute regulatory protein expression in rat granulosa cells. Toxicol Sci. 2010 Dec; 118(2):667-74.
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Sun BC, Harney JW, Berry MJ, Larsen PR. The role of the active site cysteine in catalysis by type 1 iodothyronine deiodinase. Endocrinology. 1997 Dec; 138(12):5452-8.
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Norris KC, Levine B, Ganesan K. Thyrotoxic periodic paralysis associated with hypokalemia and hypophosphatemia. Am J Kidney Dis. 1996 Aug; 28(2):270-3.