"DNA Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
| Descriptor ID |
D011088
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| MeSH Number(s) |
D08.811.074.500 D08.811.464.754.600
|
| Concept/Terms |
DNA Ligases- DNA Ligases
- Ligases, DNA
- Polydeoxyribonucleotide Ligases
- Ligases, Polydeoxyribonucleotide
- Polydeoxyribonucleotide Synthetases
- Synthetases, Polydeoxyribonucleotide
- DNA Joinases
- Joinases, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Ligases".
Below are MeSH descriptors whose meaning is more specific than "DNA Ligases".
This graph shows the total number of publications written about "DNA Ligases" by people in this website by year, and whether "DNA Ligases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2011 | 3 | 1 | 4 |
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Below are the most recent publications written about "DNA Ligases" by people in Profiles.
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Garcia AM, Salomon RN, Witsell A, Liepkalns J, Calder RB, Lee M, Lundell M, Vijg J, McVey M. Loss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila. Genome Biol. 2011 Dec 19; 12(12):R121.
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Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, Tesfaigzi Y, Gilliland FD, Belinsky SA. Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Res. 2012 Feb 01; 72(3):707-15.
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Natarajan A, Dutta K, Temel DB, Nair PA, Shuman S, Ghose R. Solution structure and DNA-binding properties of the phosphoesterase domain of DNA ligase D. Nucleic Acids Res. 2012 Mar; 40(5):2076-88.
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Dutta K, Natarajan A, Nair PA, Shuman S, Ghose R. Sequence-specific 1H, 13C and 15N assignments of the phosphoesterase (PE) domain of Pseudomonas aeruginosa DNA ligase D (LigD). Biomol NMR Assign. 2011 Oct; 5(2):151-5.
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Piserchio A, Nair PA, Shuman S, Ghose R. Solution NMR studies of Chlorella virus DNA ligase-adenylate. J Mol Biol. 2010 Jan 15; 395(2):291-308.
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Piserchio A, Nair PA, Shuman S, Ghose R. Sequence-specific 1H N, 13C, and 15N backbone resonance assignments of the 34 kDa Paramecium bursaria Chlorella virus 1 (PBCV1) DNA ligase. Biomol NMR Assign. 2009 Jun; 3(1):77-80.
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Chen D, Minami M, Henshall DC, Meller R, Kisby G, Simon RP. Upregulation of mitochondrial base-excision repair capability within rat brain after brief ischemia. J Cereb Blood Flow Metab. 2003 Jan; 23(1):88-98.
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Intano GW, McMahan CA, McCarrey JR, Walter RB, McKenna AE, Matsumoto Y, MacInnes MA, Chen DJ, Walter CA. Base excision repair is limited by different proteins in male germ cell nuclear extracts prepared from young and old mice. Mol Cell Biol. 2002 Apr; 22(7):2410-8.
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Intano GW, McMahan CA, Walter RB, McCarrey JR, Walter CA. Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity. Nucleic Acids Res. 2001 Mar 15; 29(6):1366-72.
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Mackey ZB, Ramos W, Levin DS, Walter CA, McCarrey JR, Tomkinson AE. An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Mol Cell Biol. 1997 Feb; 17(2):989-98.