Peptide Elongation Factor Tu
"Peptide Elongation Factor Tu" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
Descriptor ID |
D010444
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MeSH Number(s) |
D08.811.277.040.330.300.100.700 D12.776.157.325.150.700 D12.776.835.700.350.700
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Concept/Terms |
Peptide Elongation Factor Tu- Peptide Elongation Factor Tu
- Elongation Factor Tu
- Factor Tu, Elongation
- Protein Synthesis Elongation Factor Tu
- EF-Tu
- EF Tu
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Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor Tu".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor Tu".
This graph shows the total number of publications written about "Peptide Elongation Factor Tu" by people in this website by year, and whether "Peptide Elongation Factor Tu" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptide Elongation Factor Tu" by people in Profiles.
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Dallo SF, Zhang B, Denno J, Hong S, Tsai A, Haskins W, Ye JY, Weitao T. Association of Acinetobacter baumannii EF-Tu with cell surface, outer membrane vesicles, and fibronectin. ScientificWorldJournal. 2012; 2012:128705.
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Sharma J, Mishra BB, Li Q, Teale JM. TLR4-dependent activation of inflammatory cytokine response in macrophages by Francisella elongation factor Tu. Cell Immunol. 2011; 269(2):69-73.
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Weng G, Chen CX, Balogh-Nair V, Callender R, Manor D. Hydrogen bond interactions of G proteins with the guanine ring moiety of guanine nucleotides. Protein Sci. 1994 Jan; 3(1):22-9.
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Manor D, Weng GZ, Deng H, Cosloy S, Chen CX, Balogh-Nair V, Delaria K, Jurnak F, Callender R. An isotope edited classical Raman difference spectroscopic study of the interactions of guanine nucleotides with elongation factor Tu and H-ras p21. Biochemistry. 1991 Nov 12; 30(45):10914-20.