"Monoamine Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.
| Descriptor ID |
D008995
|
| MeSH Number(s) |
D08.811.682.664.750
|
| Concept/Terms |
Monoamine Oxidase- Monoamine Oxidase
- Oxidase, Monoamine
- Amine Oxidase (Flavin-Containing)
- MAO
- Tyramine Oxidase
- Oxidase, Tyramine
|
Below are MeSH descriptors whose meaning is more general than "Monoamine Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Monoamine Oxidase".
This graph shows the total number of publications written about "Monoamine Oxidase" by people in this website by year, and whether "Monoamine Oxidase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Monoamine Oxidase" by people in Profiles.
-
Tarpley M, Oladapo HO, Strepay D, Caligan TB, Chdid L, Shehata H, Roques JR, Thomas R, Laudeman CP, Onyenwoke RU, Darr DB, Williams KP. Identification of harmine and ?-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies. Eur J Pharm Sci. 2021 Jul 01; 162:105821.
-
Zarmouh NO, Messeha SS, Mateeva N, Gangapuram M, Flowers K, Eyunni SVK, Zhang W, Redda KK, Soliman KFA. The Antiproliferative Effects of Flavonoid MAO Inhibitors on Prostate Cancer Cells. Molecules. 2020 May 11; 25(9).
-
Zarmouh NO, Eyunni SK, Soliman KF. The Benzopyrone Biochanin-A as a reversible, competitive, and selective monoamine oxidase B inhibitor. BMC Complement Altern Med. 2017 Jan 10; 17(1):34.
-
Schmouth JF, Castellarin M, Laprise S, Banks KG, Bonaguro RJ, McInerny SC, Borretta L, Amirabbasi M, Korecki AJ, Portales-Casamar E, Wilson G, Dreolini L, Jones SJ, Wasserman WW, Goldowitz D, Holt RA, Simpson EM. Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice. BMC Biol. 2013 Oct 14; 11:106.
-
Dur?n-Gonz?lez J, Michi ED, Elorza B, Perez-C?rdova MG, Pacheco-Otalora LF, Touhami A, Paulson P, Perry G, Murray IV, Colom LV. Amyloid ? peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system. Neurobiol Aging. 2013 Aug; 34(8):2071-6.
-
Mazzio E, Deiab S, Park K, Soliman KF. High throughput screening to identify natural human monoamine oxidase B inhibitors. Phytother Res. 2013 Jun; 27(6):818-28.
-
Babu DK, Diaz A, Samikkannu T, Rao KV, Saiyed ZM, Rodriguez JW, Nair MP. Upregulation of serotonin transporter by alcohol in human dendritic cells: possible implication in neuroimmune deregulation. Alcohol Clin Exp Res. 2009 Oct; 33(10):1731-8.
-
Alford GS, Szebeni K, Klimek V, Piletz JE, Orr S, Ordway GA. Effect of smokeless tobacco extract on catecholamine metabolic enzymes in rat brain: "dippers" are getting only half of the bang. Addict Behav. 2006 Aug; 31(8):1503-9.
-
Mazzio EA, Kolta MG, Reams RR, Soliman KF. Inhibitory effects of cigarette smoke on glial inducible nitric oxide synthase and lack of protective properties against oxidative neurotoxins in vitro. Neurotoxicology. 2005 Jan; 26(1):49-62.
-
Mazzio EA, Soliman KF. Glioma cell antioxidant capacity relative to reactive oxygen species produced by dopamine. J Appl Toxicol. 2004 Mar-Apr; 24(2):99-106.