Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.

Vallecillo-Viejo IC, Liscovitch-Brauer N, Montiel-Gonzalez MF, Eisenberg E, Rosenthal JJC. Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme. RNA Biol. 2018 01 02; 15(1):104-114.

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subject areas

Adenosine
Codon, Nonsense
Cystic Fibrosis Transmembrane Conductance Regulator
Epithelial Cells
Humans
Inosine
Mutagenesis, Site-Directed
Mutation
RNA Editing
Transfection

authors with profiles

Joshua Rosenthal

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