"Inosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
| Descriptor ID |
D007288
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| MeSH Number(s) |
D03.633.100.759.590.616 D13.570.583.616 D13.570.800.573
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Inosine".
Below are MeSH descriptors whose meaning is more specific than "Inosine".
This graph shows the total number of publications written about "Inosine" by people in this website by year, and whether "Inosine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2012 | 3 | 1 | 4 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Inosine" by people in Profiles.
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Avram-Shperling A, Kopel E, Twersky I, Gabay O, Ben-David A, Karako-Lampert S, Rosenthal JJC, Levanon EY, Eisenberg E, Ben-Aroya S. Identification of exceptionally potent adenosine deaminases RNA editors from high body temperature organisms. PLoS Genet. 2023 03; 19(3):e1010661.
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Shoshan Y, Liscovitch-Brauer N, Rosenthal JJC, Eisenberg E. Adaptive Proteome Diversification by Nonsynonymous A-to-I RNA Editing in Coleoid Cephalopods. Mol Biol Evol. 2021 08 23; 38(9):3775-3788.
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Ojha N, Diaz Quiroz JF, Rosenthal JJC. In vitro and in cellula site-directed RNA editing using the ?NDD-BoxB system. Methods Enzymol. 2021; 658:335-358.
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Vallecillo-Viejo IC, Liscovitch-Brauer N, Diaz Quiroz JF, Montiel-Gonzalez MF, Nemes SE, Rangan KJ, Levinson SR, Eisenberg E, Rosenthal JJC. Spatially regulated editing of genetic information within a neuron. Nucleic Acids Res. 2020 05 07; 48(8):3999-4012.
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Montiel-Gonzalez MF, Diaz Quiroz JF, Rosenthal JJC. Current strategies for Site-Directed RNA Editing using ADARs. Methods. 2019 Mar 01; 156:16-24.
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Vallecillo-Viejo IC, Liscovitch-Brauer N, Montiel-Gonzalez MF, Eisenberg E, Rosenthal JJC. Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme. RNA Biol. 2018 01 02; 15(1):104-114.
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Alon S, Garrett SC, Levanon EY, Olson S, Graveley BR, Rosenthal JJ, Eisenberg E. The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing. Elife. 2015 Jan 08; 4.
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Lakshman MK, Kumar A, Balachandran R, Day BW, Andrei G, Snoeck R, Balzarini J. Synthesis and biological properties of C-2 triazolylinosine derivatives. J Org Chem. 2012 Jul 20; 77(14):5870-83.
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Kokatla HP, Lakshman MK. Two-step, one-pot synthesis of inosine, guanosine, and 2'-deoxyguanosine O6-ethers via intermediate O6-(benzotriazol-1-yl) derivatives. Curr Protoc Nucleic Acid Chem. 2012 Jun; Chapter 1:Unit1.26.
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Gurram V, Pottabathini N, Garlapati R, Chaudhary AB, Patro B, Lakshman MK. C-C cross-coupling reactions of O6-alkyl-2-haloinosine derivatives and a one-pot cross-coupling/O6-deprotection procedure. Chem Asian J. 2012 Aug; 7(8):1853-61.