Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen.
Thievessen I, Fakhri N, Steinwachs J, Kraus V, McIsaac RS, Gao L, Chen BC, Baird MA, Davidson MW, Betzig E, Oldenbourg R, Waterman CM, Fabry B. Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen. FASEB J. 2015 Nov; 29(11):4555-67.