Tryptophan substitutions at lipid-exposed positions of the gamma M3 transmembrane domain increase the macroscopic ionic current response of the Torpedo californica nicotinic acetylcholine receptor.

Cruz-Mart?n A, Mercado JL, Rojas LV, McNamee MG, Lasalde-Dominicci JA. Tryptophan substitutions at lipid-exposed positions of the gamma M3 transmembrane domain increase the macroscopic ionic current response of the Torpedo californica nicotinic acetylcholine receptor. J Membr Biol. 2001 Sep 01; 183(1):61-70.

View in: PubMed

subject areas

Acetylcholine
Amino Acid Substitution
Animals
Binding Sites
Cell Membrane
Gene Expression
Ion Channels
Lipid Metabolism
Models, Molecular
Mutagenesis, Site-Directed
Protein Structure, Tertiary
Receptors, Nicotinic
Torpedo
Tryptophan
Xenopus laevis

authors with profiles

Legier V. Rojas

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support