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The sigma ligand rimcazole activates noradrenergic neurons projecting to the paraventricular nucleus and increases corticosterone secretion in rats.

Eaton MJ, Lookingland KJ, Moore KE. The sigma ligand rimcazole activates noradrenergic neurons projecting to the paraventricular nucleus and increases corticosterone secretion in rats. Brain Res. 1996 Sep 16; 733(2):162-6.

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