"Pentazocine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Descriptor ID |
D010423
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MeSH Number(s) |
D03.132.577.249.106.700 D04.615.723.795.106.700
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pentazocine".
Below are MeSH descriptors whose meaning is more specific than "Pentazocine".
This graph shows the total number of publications written about "Pentazocine" by people in this website by year, and whether "Pentazocine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pentazocine" by people in Profiles.
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Robinson DL, Nag S, Mokha SS. Negative modulation of spinal ?-opioid receptor-mediated antinociception by the ?-opioid receptor at selective doses of (-)-pentazocine. Neuroreport. 2018 07 04; 29(10):852-855.
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Robinson DL, Nag S, Mokha SS. Estrogen facilitates and the kappa and mu opioid receptors mediate antinociception produced by intrathecal (-)-pentazocine in female rats. Behav Brain Res. 2016 10 01; 312:163-8.
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Eaton MJ, Lookingland KJ, Moore KE. The sigma ligand rimcazole activates noradrenergic neurons projecting to the paraventricular nucleus and increases corticosterone secretion in rats. Brain Res. 1996 Sep 16; 733(2):162-6.