"Mannitol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
Descriptor ID |
D008353
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MeSH Number(s) |
D02.033.800.609 D09.853.609
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mannitol".
Below are MeSH descriptors whose meaning is more specific than "Mannitol".
This graph shows the total number of publications written about "Mannitol" by people in this website by year, and whether "Mannitol" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2003 | 0 | 2 | 2 |
2004 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mannitol" by people in Profiles.
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Chen WL, Wang YY, Zhao A, Xia L, Xie G, Su M, Zhao L, Liu J, Qu C, Wei R, Rajani C, Ni Y, Cheng Z, Chen Z, Chen SJ, Jia W. Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential. Cancer Cell. 2016 Nov 14; 30(5):779-791.
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Kamel H, Navi BB, Nakagawa K, Hemphill JC, Ko NU. Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials. Crit Care Med. 2011 Mar; 39(3):554-9.
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Badisa VL, Latinwo LM, Odewumi CO, Ikediobi CO, Badisa RB, Ayuk-Takem LT, Nwoga J, West J. Mechanism of DNA damage by cadmium and interplay of antioxidant enzymes and agents. Environ Toxicol. 2007 Apr; 22(2):144-51.
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Kiyoshima A, Kudo K, Goto Y, Tobimatsu S, Ikeda N. Changes of the cerebral mannitol concentrations in the course of brain death of a rodent model. Leg Med (Tokyo). 2004 Apr; 6(2):117-24.
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Klimacek M, Kavanagh KL, Wilson DK, Nidetzky B. On the role of Br?nsted catalysis in Pseudomonas fluorescens mannitol 2-dehydrogenase. Biochem J. 2003 Oct 01; 375(Pt 1):141-9.
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Cucullo L, Marchi N, Marroni M, Fazio V, Namura S, Janigro D. Blood-brain barrier damage induces release of alpha2-macroglobulin. Mol Cell Proteomics. 2003 Apr; 2(4):234-41.
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Kiyoshima A, Kudo K, Nishida N, Ikeda N. HPLC simultaneous determination of glycerol and mannitol in human tissues for forensic analysis. Forensic Sci Int. 2002 Feb 18; 125(2-3):127-33.
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Kiyoshima A, Kudo K, Hino Y, Ikeda N. Sensitive and simple determination of mannitol in human brain tissues by gas chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl. 2001 Jul 05; 758(1):103-8.
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Fisher AR, Jones P, Barlow P, Kennington S, Saville S, Farrimond J, Yacoub M. The influence of mannitol on renal function during and after open-heart surgery. Perfusion. 1998 May; 13(3):181-6.